| 染色体核型分析技术的发展 |
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| 引用本文： | 徐丽霞,王秦秦.染色体核型分析技术的发展[J].医学综述,2009,15(2):188-190. |
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| 作者姓名： | 徐丽霞 王秦秦 |
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| 作者单位： | 昆明医学院第一附属医院临床实验中心,昆明,650032 |
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| 摘 要： | 各种生物染色体的形态、结构和数目都是相对稳定的。每一生物细胞内特定的染色体组成叫染色体组型,染色体组型分析也称核型分析。染色体组型分析有助于探明染色体组的演化和生物种属间的亲缘关系,对于遗传研究与人类染色体疾病的临床诊断也非常重要。染色体显带技术的产生使人们能对人类24条染色体(1～22,X,Y)进行识别和鉴定,而且近年来已经可以通过计算机软件进行自动核型分析。
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| 关 键 词： | 核型分析 光谱核型分析 荧光原位杂交 GRQ带技术 |
Development of Chromosome Karyctype Analysis Technology |
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| XU Li-xia,WANG Qin-qin.Development of Chromosome Karyctype Analysis Technology[J].Medical Recapitulate,2009,15(2):188-190. |
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| Authors: | XU Li-xia WANG Qin-qin |
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| Institution: | XU Li-xia , WANG Qin-qin. ( Center of Medical Research,the First Affiliated Hospital of Kunming Medical College,Kunming 650032, China) |
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| Abstract: | The form,texture and amount of chromosome keep constant among various kinds of organisms. The chromosome constitution for each organism is called for karyotype. Idiogram analysis, i. e. karyotype analysis, make for probe chromosome evolution and kinship among biological species. Furthermore, it is very important for research of genetics and clinical diagnosis of mankind chromosomal disease. Chromosome banding technology is helpful in identification of 24 human chromosomes （ 1 - 22, X, Y）, and the karyotype has been analyzed auto-matically by computer software in recent years. |
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| Keywords: | Karyotype analysis Spectral karyotyping Fluorescence in situ hybridization GRQ technology |
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