The neurological mutation staggerer is expressed in embryonic cerebellar transplants matured in the anterior eye chamber of normal mice |
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Authors: | W Wille D Goldowitz A Seiger L Olson |
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Affiliation: | 1. Departments of Ophthalmology, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamikyo-ku, Kyoto 602 Japan;2. Department of Anatomy, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamikyo-ku, Kyoto 602 Japan |
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Abstract: | Horseradish peroxidase (HRP)-filled neurons and their processes were consistently detected in the ventral portion of the dog hypothalamus after intraocular injection of HRP. The number of HRP-filled neurons decreased in parallel with the extent of the resection of the optic nerve. HRP-filled neurons were never detected in specimens with a complete resection of the optic nerve. These findings strongly indicate that these HRP-filled neurons in the ventral hypothalamus are the source of centrifugal fibers to the retina. |
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Keywords: | hypothalamo-retinal pathway centrifugal fibers horseradish peroxidase tracing dog |
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