冠心病患者中心动脉压与肱踝脉搏波速度的相关性研究

目的探讨冠心病患者中心动脉压（CAP）与肱一踝脉搏波速度（baPWV）的相关性。方法选择冠状动脉造影（CAG）检查患者100例，按冠心病诊断标准分为冠心病组65例，非冠心病组35例。记录血管造影过程中检测到的升主动脉压力作为CAP，并采用全自动动脉硬化检测仪测定baPWV。结果①冠心病组较非冠心病组CSP、baPWV、TC、LDL—C水平有统计学差异（P〈O．05）。②多元线性逐步回归分析显示年龄、CSP、CDP、FBG和LDL—C是baPWV的独立影响因素。结论冠心病患者CAP升高，进～步促进了主动脉管壁弹性下降，中心动脉僵硬度增高，而年龄、中心动脉压、FBG、LDL—C是影响动脉僵硬度的独立危险因素。

Research of relation between central artery pressure and brachial-ankle pulse wave velocity in patients with coronary artery disease

Objective To study the relation of central artery pressure （CAP） and brachial-ankle pulse wave velocity （baPWV） in patients with coronary artery disease （CAD）. Methods One hundred patients who underwent coronary angiogra- phy （CAG） were subjected and divided into CAD group（n=65）, and control group（n=35）. Central aortic pressure was invasive- ly determined by catheterization and baPWV was measured with a PWV device. Results （~）The central artery systolic pressure （CSP）, TC, LDL-C and baPWV were significandy higher in CAD group than that in control group （P〈0.05）. （~）Muhiple linear regression analysis showed that age, CSP,CDP, FBG and LDI-C were the independent risk factors for baPWV. Conclusion The central artery pressure is significantly higher in patients with CAD, promoting further artery elasticity decrease. Age, CAP, FBG and LDL-C are the independent risk factors for arterial stiffness.