利用激光多普勒血流仪测定氯化钠高渗液置圆窗对耳蜗血流 …

目的：研究０．５ｍｏｌ／Ｌ，１．５ｍｏｌ／Ｌ和６．１ｍｏｌ／Ｌ高渗在ＮａＣｌ溶液置栗鼠对耳蜗血流的影响。方法：动物全身麻醉，暴露圆窜犯分别放置０．５ｍｏｌ／Ｌ，１．５ｍｏｌ／Ｌ、６．１ｍｏｌ／Ｌ的ＮａＣｌ溶液棉片，利用激光多普勒血流仪测定２ｈ内耳蜗血流（ＣＢＦ）改变情况，结果：０．５ｍｏｌ／Ｌ，１．５ｍｏｌ／Ｌ和６．１ｍｏｌ／Ｌ三种ＮａＣｌ溶液分别可提高ＣＢＦ７．６％，２４．５％和３５．３％。结论

The influence on cochlear blood flow and inner ear elect rophysiology after placing NaCl osmotic solution in round window of Chinchilla

Aim The influence on inner ear electrophysiology and cochlear blood flow caused by placing osmotic NaCl solution in round window was observed. Methods The cotton pieces absorbed NaCl osmotic solution (0.5 mol/L, 1.5 mol/L, 6.1 mol/L) were put on round windows of Chinchillas under general anesthesia separately. The changes of cochlear blood flow (CBF) and cochlear action potential (CAP) were observed. Results The 0.5 mol/L, 1.5 mol/L solution and 6.1 mol/L solution could enhance the CBF to 7.6%, 24.5% and 35.3% separately. After placing 1.5 mol/L solution and 6.1mol/L solution the threshold of CAP rose obviously,especially in the field of high frequency. The threshold shift of CAP caused by 0.5mol/L solution was not notable. Conclusion This experiment confirmed that NaCl solution could improve the circulation of inner ear. The influence of NaCl osmotic solution on hearing were getting serious with concentration rising.