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荷叶对家兔食饵性高胆固醇血症和动脉粥样硬化影响
引用本文:吴吉茂,史玉梅,刘秋如,黄学顺,赵丹丹.荷叶对家兔食饵性高胆固醇血症和动脉粥样硬化影响[J].江西医学院学报,1987(3).
作者姓名:吴吉茂  史玉梅  刘秋如  黄学顺  赵丹丹
作者单位:江西医学院病理生理学教研室,江西医学院病理生理学教研室,江西医学院病理生理学教研室,江西医学院病理生理学教研室,江西医学院病理生理学教研室
摘    要:本文观察了荷叶对家兔喂高胆固醇饲料引起的高胆固醇血症和动脉粥样硬化形成的影响。实验结果:服荷叶组血清胆固醇水平明显低于对照组(P<0.05),其主动脉粥样硬化斑块明显小于对照组(P<0.05)。此结果表明,荷叶不仅能抑制家兔喂高胆固醇饲料引起的高胆固醇血症,而且能抑制动脉粥样硬化的形成。简要地讨论了荷叶上述作用的可能机制。

关 键 词:高胆固醇血症/药物疗法  动脉粥样硬化/药物疗法  动物  实验  家兔  荷叶/药效学

The Effect of Folium Nelumbinis on Hypercholesteremia and Atherosclerosis in Rabbits Fed with High Cholesteral Diet
Wu Jimao,Shi Yimei,Liu Qiuru,Huang Xueshun,Zhao Dandan.The Effect of Folium Nelumbinis on Hypercholesteremia and Atherosclerosis in Rabbits Fed with High Cholesteral Diet[J].Acta Academiae Medicinae Jiangxi,1987(3).
Authors:Wu Jimao  Shi Yimei  Liu Qiuru  Huang Xueshun  Zhao Dandan
Institution:Wu Jimao,Shi Yimei,Liu Qiuru,Huang Xueshun,Zhao Dandan Department of Pathophysiology,Jiangxi Medical College,Nanchang
Abstract:The effect of Folium Nelumbinis on hypercholesteremia and atherosclero- sis in rabbits fed with high cholesterol deit has been observed. The serum cholesterol level in Folium Nelumbinis-treated group was much lower than that in control group (P<0.05), and the area of lipid pleques formed in the intima of the aorta in treated group was also less than that in control group (P<0.05). These results indicated that Folium Nelumbinis not only Could inhibit hypercholesteremia in rabbits fed with high cholesterol diet but also markedly inhibit the formation of atherosclerosis in this group. Its possible mechanism has been discussed briefly.
Keywords:hypercholesteremia/drug theragy  atherosclerosis/durg therapy  animals  laboratory  rabbit  Folium Nelumbinis/pharmacodynamics
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