小儿过敏性紫癜性肾炎肾脏病理分级与中医辨证的关系

目的探讨小儿过敏性紫癜性肾炎肾脏病理分级与中医辨证分型的关系。方法对114例小儿过敏性紫癜（血尿伴蛋白尿型）患儿肾组织活体检查结果与中医证型的关系进行研究。结果中医辨证分型中,血热夹瘀型最多,构成比为0.614 0,其次为阴虚夹瘀型（构成比为0.245 6）、风热夹瘀型（构成比为0.096 5）,气阴两虚夹瘀型（构成比为0.043 9）。病理分级以Ⅲ级病变为最多,构成比为0.561 4,其中Ⅲa型最为常见,构成比约为0.412 3。结论目前中医水肿辨证分型并不完全适用于过敏性紫癜性肾炎的辨证,应加强对血瘀证的认识。

Relationship between Renal Pathology Classification and Traditional Chinese Medicine Syndrome Types in Children Henoch-Sch-nlein Purpura Nephritis

Objective To explore the relationship between traditional Chinese medicine(TCM) syndrome types and renal pathology classification in children with Henoch-Schnlein purpura nephritis(HSPN).Methods The relationship between biopsy results of renal tissues and TCM syndrome types was studied in 114 children with HSPN characterized by hematuria complicated with proteinuria.Results Among TCM syndrome types,blood-heat complicated with blood stasis syndrome ranked first,with constituent ratio being 0.6140,followed by yin-deficiency complicated with blood stasis syndrome(constituent ratio being 0.2456),wind-heat complicated with blood-stasis syndrome(constituent ratio being 0.096 5),and qi-yin deficiency complicated with blood-stasis syndrome(constituent ratio being 0.0439).In pathological grading,grade Ⅲ ranked first,with constituent ratio being 0.561 4;among pathological grade Ⅲ,grade Ⅲa was the most common,with constituent ratio being 0.412 3.Conclusion At present,the TCM syndrome types of edema is not completely fit for HSPN;therefore,some attentions should be paid to differentiating the blood-stasis syndrome.