| 高胆红素血症新生儿总胆红素/白蛋白比值与脑干听觉诱发电位的关系 |
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| 引用本文： | 刘辉,潘家华,闵红,周晓丽. 高胆红素血症新生儿总胆红素/白蛋白比值与脑干听觉诱发电位的关系[J]. 临床儿科杂志, 2011, 29(9). DOI: 10.3969/j.issn.1000-3606.2011.09.012 |
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| 作者姓名： | 刘辉 潘家华 闵红 周晓丽 |
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| 作者单位： | 安徽省立医院儿科,安徽合肥,230001 |
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| 摘 要： | 目的 探讨总胆红素/白蛋白比值与脑干听觉诱发电位(BAEP)的相关性及其预测高胆红素血症新生儿听力损害的临床价值.方法 检测113例新生儿的总胆红素(TSB)、白蛋白水平,计算总胆红素/白蛋白比值(B/A),将B/A值≥ 3.0 × 10-3的83例新生儿作为观察组,并根据B/A值分4个亚组;另30例B/A ﹤ 3.0 × 10-3的新生儿作为对照组.检测所有新生儿的BAEP,分析TSB水平、B/A值与BAEP异常的相关性.结果 观察组各亚组间新生儿的BAEP异常率差异有统计学意义(P ＜ 0.01),随B/A值增大,BAEP异常率增高;观察组各亚组间新生儿BAEP的Ⅴ波潜伏期及Ⅰ-Ⅴ、Ⅲ-Ⅴ波间期的差异有统计学意义(P均＜ 0.05);TSB水平、B/A值的工作特征曲线(ROC)下面积(AUC)差异也有统计学意义(P ＜ 0.05);BAEP异常与B/A值密切相关(χ2 ＝ 13.489,P ＜ 0.05).结论 B/A值与BAEP异常相关性高,具有预测高胆红素血症新生儿听力损害的临床价值.
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| 关 键 词： | 总胆红素/白蛋白 脑干听觉诱发电位 高胆红素血症 新生儿 |
Correlation of bilirubin/albumin ratio and brainstem auditory evoked potential in infants with hyperbilirubinemia |
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| LIU Hui,PAN Jia-hua,MIN Hong,ZHOU Xiao-li. Correlation of bilirubin/albumin ratio and brainstem auditory evoked potential in infants with hyperbilirubinemia[J]. The Journal of Clinical Pediatrics, 2011, 29(9). DOI: 10.3969/j.issn.1000-3606.2011.09.012 |
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| Authors: | LIU Hui PAN Jia-hua MIN Hong ZHOU Xiao-li |
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| Affiliation: | LIU Hui,PAN Jia-hua,MIN Hong,ZHOU Xiao-li(Department of Pediatrics,Anhui Provincial People's Hospital,Hefei 230001,Anhui,China) |
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| Abstract: | Objective To assess the clinical value of bilirubin /albumin(B/A)ratio in predicting bilirubin-induced auditory impairment,and its correlation with brainstem auditory evoked potential(BAEP)in full-term neonates with jaundice.Methods One hundred and thirteen infants'peripheral blood specimens were obtained to determine B/A ratio,indrect serum bilirubin and total serum bilirubin(TSB).Hereinto 83 jaundice infants were enrolled as case group and stratified into 4 subgroups based on their levels of B/A ratio(sub... |
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| Keywords: | bilirubin/albumin ratio brainstem auditory evoked potential hyperbilirubinemia newborn |
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