龙胆泻肝汤合葛根方辅助治疗突发性耳聋

目的:探讨龙胆泻肝汤合葛根方辅助西医治疗突发性耳聋的临床疗效及机制。方法:选取海南省中医院2013年1月—2014年12月收治的突发性耳聋患者110例,采用随机抽签法分为对照组和治疗组,各55例;对照组患者采用西医常规药物治疗,治疗组患者在对照组治疗基础上加用龙胆泻肝汤合葛根方辅助治疗;比较两组患者临床疗效、病症消失率、治疗前后听力损失分值、纯音听阈值、耳鸣分级水平及血液流变学指标水平等。结果:对照组和治疗组患者临床治疗总有效率分别为80.00%,90.91%;治疗组患者临床疗效明显优于对照组(P0.05);治疗组患者病症消失率明显高于对照组(P0.05);治疗组患者治疗后听力损失分值和纯音听阈值均明显低于对照组、治疗前(P0.05);治疗组患者治疗后耳鸣分级情况明显优于对照组、治疗前(P0.05);治疗组患者治疗后血液流变学指标水平均明显低于对照组、治疗前(P0.05)。结论:龙胆泻肝汤合葛根方辅助西医治疗突发性耳聋可有效促进听力恢复,降低听力损失,并有助于缓解耳鸣症状。

Longdan Xiegan Tang and Gegen Fang in Assisting Western Medicine for Sudden Deafness

Objective: To investigate the clinical effects of Longdan Xiegan Tang and Gegen Fang in assisting western medicine for sudden deafness. Method: The 110 patients with sudden deafness from January 2013 to December 2014 in Hainan Hospital of Traditional Chinese Medicine were selected and randomly divided into control group (55 patients) with conventional western medicine treatment and treatment group (55 patients) with Longdan Xiegan Tang and Gegen Fang based on the treatment in control group. The clinical efficacy,the symptom disappearance rate,the hearing loss values,pure tone threshold value,the level of tinnitus grading state and blood rheology index before and after treatment of two groups were compared. Result: The total effective rate was 80.00% and 90.91% in control group and treatment group respectively. The clinical efficacy in treatment group was significantly superior to that in control group(P < 0.05). The symptom disappearance rate of treatment group was significantly higher than that of control group(P < 0.05). The hearing loss value and pure tone threshold value in treatment group after treatment were significantly lower than those in control group and before treatment (P < 0.05). The level of tinnitus grading state in treatment group after treatment was significantly higher than that in control group and before treatment(P < 0.05). The level of blood rheology index in treatment group after treatment was significantly lower than that in control group and before treatment(P < 0.05). Conclusion: Longdan Xiegan Tang and Gegen Fang in assisting western medicine for sudden deafness can efficiently accelerate the recovery process of hearing,reduce the hearing loss degree and help to alleviate the symptoms of tinnitus.