| 头孢哌酮/舒巴坦对346株革兰阴性杆菌抗菌活性的分析 |
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| 引用本文： | 杨娟,周静.头孢哌酮/舒巴坦对346株革兰阴性杆菌抗菌活性的分析[J].中国医院用药评价与分析,2010(5):451-453. |
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| 作者姓名： | 杨娟 周静 |
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| 作者单位： | 新疆心脑血管病医院检验科; |
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| 摘 要： | 目的：调查头孢哌酮/舒巴坦对医院常见革兰阴性杆菌的体外抗菌活性。方法：收集我院2007年1月～2009年12月从临床标本中分离到的革兰阴性杆菌346株,采用VITEK-32全自动微生物分析仪进行鉴定,用K-B纸片法对头孢哌酮/舒巴坦进行药敏实验。结果：医院肠杆菌科细菌以肺炎克雷伯菌、大肠埃希菌、阴沟肠杆菌为主;其对头孢哌酮/舒巴坦的耐药率分别为9.6%、3.2%、8.7%。非发酵菌以铜绿假单胞菌、鲍曼不动杆菌、嗜麦芽寡养单胞菌为主,其对头孢哌酮/舒巴坦的耐药率分别为33.7%、17.1%、50%。结论：除嗜麦芽寡养单胞菌外,其余革兰阴性杆菌耐药率均〈40%,头孢哌酮/舒巴坦具有很强的体外抗菌活性,是治疗革兰阴性杆菌感染的理想药物。
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| 关 键 词： | 革兰阴性杆菌 头孢哌酮/舒巴坦 耐药性 |
Antimicrobial Activity of Cefoperzone /Sulbactam Against 346 Strains of Gram-negative Bacilli |
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| YANG Juan,ZHOU Jing.Antimicrobial Activity of Cefoperzone /Sulbactam Against 346 Strains of Gram-negative Bacilli[J].Evaluation and Analysis of Drug-Use in Hospital of China,2010(5):451-453. |
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| Authors: | YANG Juan ZHOU Jing |
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| Institution: | YANG Juan,ZHOU Jing ( Dept. of Clinical Laboratory,Xinjiang Hospital of Cardio-Cerebro Vascular Diseases,Urumqi 830011,China) |
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| Abstract: | OBJECTIVE: To investigate the in vitro antibacterial activity of cefoperazone /sulbactam bacilli against the common gram negative bacilli. METHODS: A total of 346 strains of gram-negative bacilli isolated in our hospital from Jan. 2007 to Dec. 2009 were identified with the use of VITEK-32 full automated microbiology analyzer. Antimicrobial susceptibility was detected by K-B disk diffusion test. RESULTS: The primary Enterobacteriaceae were Klebsiella pneumoniae Escherichia coli and Enterobacter cloacae,and t... |
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| Keywords: | Gram-negative bacilli Cefoperazone /sulbactam Drug resistance |
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