| 脾虚大鼠脑神经生化指标变化的实验研究 |
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| 引用本文： | 邓月娥,纪立金.脾虚大鼠脑神经生化指标变化的实验研究[J].福建中医学院学报,2006,16(2):49-50,61. |
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| 作者姓名： | 邓月娥 纪立金 |
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| 作者单位： | 福建中医学院中医系,福建,福州,350108 |
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| 基金项目： | 福建省青年科技人才创新基金 |
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| 摘 要： | 研究中医脾虚证对大鼠脑记忆功能生化指标的影响.用泻下和劳倦法制作脾虚大鼠模型,再用四君子汤治疗,检测大鼠的脑生化指标.结果：脾虚组AchE明显升高,与正常组比较差异非常显著（P＜0.01）,与四君子汤治疗组比较,差异显著（P＜0.05）;脾虚组NO含量、NOS活性明显较正常组及四君子汤治疗组低（P＜0.05）.结论：脾虚影响大鼠脑记忆功能的生化指标.
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| 关 键 词： | 脾虚 四君子汤 乙酰胆碱酯酶 一氧化氮合成酶 一氧化氮 大鼠 |
| 文章编号： | 1004-5627（2006）02-0049-02 |
| 收稿时间： | 2005-04-22 |
| 修稿时间： | 2005-04-22 |
Experimental Study on the Changes of Biochemical Indicators of Cerebral Nerves in Spleen Deficiency Rats |
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| DENG Yue-e,JI Li-jin.Experimental Study on the Changes of Biochemical Indicators of Cerebral Nerves in Spleen Deficiency Rats[J].Journal of Fujian College of Traditional Chinese Medicine,2006,16(2):49-50,61. |
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| Authors: | DENG Yue-e JI Li-jin |
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| Institution: | Department of TCM, FCTCM, Fuzhou, Fujian 350108, China |
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| Abstract: | To investigate the influence of spleen deficiency on memory.The model rats of spleen deficiency were made by diarrhea and fatigue,and then were administered sijunzi decoction,the levels of AchE,NOS,NO in the brain tissue were tested.The result showed that the levels of AchE in spleen deficiency group were obviously higher than that of control group and sijunzi decoction group(P<0.01,P<0.05),and NOS,NO was significantly lower than that of another two groups(P<0.05).Conclusions: Spleen deficiency depresses rats' ability of learning and memory. |
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| Keywords: | spleen deficiency sijunzi decoction acetylcholinesterase nitric oxide synthetase nitric oxide rat |
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