静滴硝酸甘油与口服长效消心痛治疗急性心肌梗塞的疗效观察

我们观察了静滴硝酸甘油及口服长效消心痛对５８例急性心肌梗塞病人梗塞后心绞痛、ＳＴ段变化及心功能的影响。结果显示：静滴硝酸甘油控制梗塞后心绞痛的发生和持续时间比口服长效消心痛显著有效（Ｐ＜０．０１）；对入院后２４ｈ、４８ｈ的ΣＳＴ及入院后２４ｈＮＳＴ的变化两组无显著差异（Ｐ＞０．０５）；对入院后４８ｈ的ＮＳＴ的减少及入院后两周的心功能改善则前者显著优于后者（Ｐ＜０．０１）。

CLINICAL EFFICACY OF INTRAVENOUS NITROGLYCERINE AND ORAL SLOW-RELEASE ISOSORBIDE DINITRATE ON ACUTE MYOCARDIAL INFARCTION

The effects of intravenous nitroglycerine and oral slow-release isosorbidedinitrate on postinfarction angina pectoris ,changes of ST segments and cardiac function wereobserved in 58 patients with acute myocardial infarction。 The results show :intravenous nitro-glycerine is more effective than oral slow-release isosorbide dinitrate in controlling occur-rence and lasting time of postinfarction angina pectoris(P< 0.01). The differences of bothgroups in ΣST changes at the twenty-fourth hour and the forty-eighth hour after admissionand in NST changes at the twenty-fourth hour after admission are insignificant ( P > 0.05)。However,in decrease of NST at the forty-eighth hour after admission and in improvement ofcardiac function in two weeks after admission, intraverous nitroglycerine is better than oralslow-release isosorbide dinitrate (P(0.01)