| 纤维蛋白凝胶在心肌梗死治疗中的应用进展 |
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| 引用本文： | 张雪莲. 纤维蛋白凝胶在心肌梗死治疗中的应用进展[J]. 心血管病学进展, 2010, 31(2): 245-247. DOI: 10.3969/j.issn.1004-3934.2010.02.029 |
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| 作者姓名： | 张雪莲 |
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| 作者单位： | 新疆医科大学第一附属医院心脏中心冠心病科,新疆,乌鲁木齐,830054 |
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| 基金项目： | 新疆维吾尔自治区科技支疆项目 |
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| 摘 要： | 采用组织工程技术和生物材料对心肌梗死后受损的心肌进行修复是近年来研究的热点。纤维蛋白凝胶作为一种支架材料在组织工程领域得到广泛地应用。它既承担了输送细胞和蛋白质等的载体作用,又起到了提供细胞外基质的作用,促进了细胞的增殖与分化。现主要从纤维蛋白凝胶的结构特性及在治疗心肌梗死中的应用做一综述。
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| 关 键 词： | 纤维蛋白凝胶 组织工程心肌 心肌梗死 |
Application of Fibrin Gel in Myocardial Infarction |
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| ZHANG Xue-lian. Application of Fibrin Gel in Myocardial Infarction[J]. Advances in Cardiovascular Diseases, 2010, 31(2): 245-247. DOI: 10.3969/j.issn.1004-3934.2010.02.029 |
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| Authors: | ZHANG Xue-lian |
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| Affiliation: | ZHANG Xue-lian,MA Yi-tong (Department of Cardiology,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China ) |
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| Abstract: | The technique of combining cells and biomaterial in order to repair damaged myocardium postinfarction is becoming popular.Fibrin gel is being used extensively as a biopolymer scaffold for this engineering.Fibrin gel may work as a vehicle for delivering both cells and protein,and providing an extracellular matrix which can promote cell proliferation and differentiation.In this review we have summarized the properties of fibrin gel,and its applications in myocardial infarction. |
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| Keywords: | fibrin gel cardiac tissue engineering myocardial infarction |
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