| 呼吸道合胞病毒(RSV)与Th1/Th2细胞因子的关系研究进展 |
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| 引用本文： | 张竞,阎浩林,梅兴国. 呼吸道合胞病毒(RSV)与Th1/Th2细胞因子的关系研究进展[J]. 沈阳药科大学学报, 2008, 25(12): 1016-1020 |
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| 作者姓名： | 张竞 阎浩林 梅兴国 |
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| 作者单位： | 沈阳药科大学生命科学与生物制药学院，军事医学科学院毒物药物研究所 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 目的对感染呼吸道合胞病毒产生的Th1、Th2型细胞因子种类及其对Th1/Th2型反应平衡的影响进行综述。方法在查阅国内外文献的基础上,介绍各种细胞因子在呼吸道合胞病毒(RSV)感染中的作用、地位。结果与结论虽然到目前为止各种细胞因子在各实验中得出的结果,甚者是对于RSV感染更倾向于发生Th1型还是Th2型反应仍有争论,但Th1/Th2反应平衡在RSV治疗和开发防治药物方面仍具有重要意义。
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| 关 键 词： | 呼吸道合胞病毒 Th1/Th2型细胞因子 Th1/Th2平衡 |
| 收稿时间： | 2008-01-16 |
Development on the relationship between rspiratory syncytial virus and Th1/Th2 cytokines |
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| ZHANG Jing,YAN Hao-lin,MEI Xing-guo. Development on the relationship between rspiratory syncytial virus and Th1/Th2 cytokines[J]. Journal of Shenyang Pharmaceutical University, 2008, 25(12): 1016-1020 |
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| Authors: | ZHANG Jing YAN Hao-lin MEI Xing-guo |
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| Affiliation: | 1.School of Life and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, China；2.Institute of Toxicology and Pharmacology, Academy of Military Medical Sciences，Beijing 100850, China |
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| Abstract: | Objective To sum up the variety of Th1/Th2 cytokines and the balance of Th1/Th2 immune reaction when infectd by the respiratory syncytial virus(RSV).Methods The production,classification and the action of cytokines after RSV infection were summarized on the basis of thirty papers published recently.Results and Conclusions The roles of different kinds of Th1/Th2 cytokines in RSV infection were introduced specifically.Althaugh some of these studies had very different purposes and results,they all indicated that these cytokines and the balance of Th1/Th2 were very important for the treatment of RSV and the development on the prophylaatic and curative agent of RSV. |
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| Keywords: | respiratory syncytial virus Th1/Th2 cytokines Th1/Th2 balance |
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