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Zootoxicological properties of venom L-amino acid oxidase |
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| Authors: | Findlay E. Russell Fred W. Buess Moon Y. Woo Ronaldine Eventov |
| Affiliation: | a Laboratory of Neurological Research, Loma Linda University, Los Angeles County Hospital, Los Angeles, California, USA b Department of Zoology, University of Cambridge, England |
| Abstract: | L-amino acid oxidase prepared from Crotalus adamanteus venom after the method of Wellner and Meister does not contribute to the production of the profound fall in systemic arterial pressure usually seen following injection of crude Crotalus venom, nor does it provoke any early deleterious changes in the dependent variables of the cardiovascular system.The enzyme has no effect on neuromuscular transmission in the mammal. Its LD50 is 9·13 (7·83–10·35) mg per kg test animal body weight. |
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