肾移植受体术后死亡原因分析及预防措施探讨

目的 总结肾移植受体术后死亡原因,探讨其预防措施。方 法 回顾性分析2007年8月至2013年3月在安徽医科大学第一附属医院泌尿外科接受肾移植术的6例术后死亡病例的临床资料,结合文献分析死亡原因。结果 6例死亡病例中,因移植失败或反复并发症放弃治疗死亡3例,急性心血管事件1例,肺部感染死亡1例,暴发性肝衰竭死亡1例。结论 放弃治疗、肺部感染、急性心血管事件和暴发性肝衰竭是肾移植受体术后死亡的重要原因。放弃治疗的原因是移植失败或移植后反复出现并发症。医师争取家属的配合,共同对患者加强心理疏导、敦促其配合治疗是防治的重要措施。

Analysis of the causes of death and preventive measures in renal transplant recipients

Objective To analyze the cause of death in renal transplant recipients and to investigate the preventive measures. Methods Clinical data of 6 death cases were retrospectively analyzed, who underwent renal transplantation in the Department of Urinary Surgery of the First Affiliated Hospital of Anhui Medical University from August 2007 to March 2013. The causes of death were analyzed combined with associated literatures. Results In 6 dead cases, the causes of death were abandoning treatment for graft failure or repeated complication in 3 cases, acute cardiovascular event in 1 case, pulmonai~~ infection in 1 case, and fulminant hepatic failure in 1 case. Conclusions Abandoning treatment, pulmonary infection, acute cardiovascular event and fuiminant hepatic failure are the important reasons for death of renal transplant recipients. The reason of abandoning treatment is graft failure or repeated complication after transplantation. It is an important preventing measure that physicians cooperate with family members to strengthen the psychological counseling with patients and prompt them to comply the treatments.