基于服药依从性的主动式干预对社区精神分裂症患者康复的影响

目的探讨聚焦服药依从性的主动式干预对社区精神分裂症患者康复效果的影响。方法选取2019年6月—12月上海市普陀区社区内符合精神分裂症诊断的病例，采用随机抽样方法，选取患者120例，分为研究组和对照组,各60例。对照组仅予常规抗精神病药物治疗与门诊随访，研究组在此基础上,进行服药依从性的主动式干预，为期24个月,比较两组患者阴性和阳性症状量表(PANSS)、个人和社会功能量表(PSP)评分以及服药依从性、复发等变化情况。结果实际完成研究组57例，对照组54例。干预24个月后，研究组PANSS、PSP量表评分与对照组比较均有变化，差异具有统计学意义(P<0.05)。研究组干预前后自身比较显示，患者PANSS、PSP量表评分以及服药依从性差异有统计学意义(P<0.05)。结论在药物治疗的基础上进行服药依从性的主动式干预模式，对于社区精神分裂症患者控制病情,提高服药依从性，恢复社会功能,减少复发具有积极作用，对疾病的远期疗效具有促进作用，能提高患者的生存质量。

Effect of active intervention of medication compliance on rehabilitation of schizophrenic patients in community

ObjectiveTo explore the effect of active intervention focusing on medication compliance on rehabilitation of schizophrenic patients in community. MethodsFrom June 2019 to December 2019, 120 community-dwelling schizophrenia patients in Shanghai Putuo District were randomly divided into the study group and the control group with 60 cases in each group. The control group was treated with conventional antipsychotic drugs, while the study group was also given active intervention of medication compliance for 24 months in addition to routine treatment. The scores of Positive and Negative Symptom Scale(PANSS), Personal and Social Functioning Scale(PSP), medication compliance and recurrence were compared between two groups. ResultsFifty-seven cases in the study group and 54 cases in the control group were followed up. Compared with those before intervention the PANSS and PSP scale scores were significantly decreased and medication compliance rate of the study group were significantly increased after 24 months of intervention(all P<0.05); and the above indicators were also better than those of the control group(all P<0.05). ConclusionOn the basis of drug therapy, the active intervention of medication compliance has a positive effect on the medication compliance and disease control for community-dwelling schizophrenia patients.