儿童唾液变形链球菌与患龋状况关系的研究

目的：探讨唾液变形链球菌与儿童龋病的关系。方法：通过口腔健康检查,问卷调查等全面了解并分析350名3～7岁在园儿童龋患情况及影响乳牙龋病发生的危险因素。采用直接接种轻唾培养基法检测唾液中变形链球菌浓度,探讨其与患龋情况的关系。结果：350名被检儿童中263名患龋,总患龋率75.14%,龋均4.73,龋面均11.11。单因素分析显示年龄、牛奶或饮用水加糖、吃甜食及糖果糕点次数、父亲刷牙情况及月家庭经济收入与儿童的龋患程度相关（P〈0.05）。多因素回归分析显示年龄、牛奶或饮水加糖、每日进食糖果糕点次数、父亲刷牙情况是乳牙龋的重要影响因素。350例儿童唾液变形链球菌菌落数中位数为1.61×105 CFU/mL,无龋（dmfs=0）、低龋（1≤dmft〈6）、高龋（dmfs≥6）儿童间变形链球菌浓度差异有统计学意义（P〈0.05）。其中184名早期入园的儿童通过为期一年的追踪观察显示唾液变形链球菌浓度与新增dmfs呈正相关关系。结论：儿童唾液变形链球菌浓度与龋患严重程度以及龋活跃性相关。

Relationship between the Streptococcus Mutans levels in saliva and the dental caries status of children

Objective:To investigate the salivary Streptococcus mutans(S.m) levels in children and its association with caries status.Method:350 children aged from 3 to 7 years-old in kindergartens were included in this study.Oral examination was carried out and recorded carefully for caries status;Questionnaire was designed to investigate the caries related factors of society and behavior.S.m were culured and isolated by MS to measure the salivary S.m levels,and the relationship between salivary S.m load and caries st...