冠脉侧支血流分数与急性心肌梗死关系研究

目的研究侧支循环与急性心肌梗死（AMI）介入术（PCI）后左室功能变化之间的关系。方法AMI患者29例行急诊PCI，术中应用冠脉内压力导丝测定冠状动脉内压力，计算压力源性的侧支血流分数（PDCF）．依据冠脉侧支血流是否充盈，以0．24为PDCF截值将样本分为两组，术后采用Simpson方法测定左室射血分数（LVEF）、左室收缩及舒张末期容积（ESV、EDV），并计算相关的容积指数（ESVI、EDVI）。结果两组患者的PDCF均与PCI术后30d时的射血分数呈正相关（r=0．9，P〈0．01）。结论冠脉内压力源性的PDCF可预测AMI时左室功能的恢复情况。

Correlation between pressure-derived collateral fractional flow and acute myocardial infarction

Objective To measure the pressure-derived collateral fractional flow(PDCF) in the patients with acute myocardial infarction(AMI),and to evaluate the correlation between PDCF and left ventricular recovery function after primary percutaneous coronary intervention(PCI).Methods The PDCF,determined by Pw/Pa,was measured in 29 patients with first AMI treated by primary PCI,who were devided into two groups by the PDCF=0.24.Left ventricular ejection fraction(LVEF),end systolic volume(ESV) and end diastolic volume(EDV),and the related indexes were obtained by Simpson method after PCI.Results LVEF in both groups were significantly related to PDCF in the 30th day(R=0.9,P<0.01) after PCI.Conclusion The collateral blood flow,as measured by PDCF,can predict left ventricular recovery function after successful PCI.