中药辨证论治联合西药常规治疗急性胰腺炎

目的:观察中药辨证论治联合西药常规治疗急性胰腺炎( acute pancreatitis,AP)的临床疗效.方法:将符合病例入选标准的80例AP患者随机分为观察组、对照组各40例.两组患者均在监护情况下给予禁食,胃肠减压,纠正水、电解质紊乱,调节酸碱平衡；抑制胃酸、胰酶分泌,抗感染,解痉止痛等对症治疗.观察组在此基础上给予中药辨证论治,1剂/d,水煎取汁分2～3次口服或鼻饲.2组均以7d为1个疗程.结果:痊愈率观察组55.00％,对照组42.50％ (P ＜0.05)；总有效率观察组92.50％,对照组77.50％(P＜0.05).腹胀、腹痛、发热、大便不通等临床症状消失时间观察组分别为(3.08 ±1.83),(2.33±1.22),(2.54±1.67),(1.18±0.42)d,对照组分别为(5.14±1.78),(4.57±1.30),(6.93±1.88),(3.22±0.85)d,观察组优于对照组(P＜0.05).C反应蛋白( CRP)、血淀粉酶、血脂肪酶复常时间,住院时间观察组分别为(6.11±1.53),(4.48±1.86),(4.64±1.64),(8.53±2.42)d,对照组分别为(9.56±2.68),(8.63±1.98),(7.05±1.84),(13.48±3.67)d,观察组优于对照组(P＜0.05).结论:中药辨证论治联合西药常规治疗AP临床疗效显著,腹胀、腹痛、发热、大便不通等临床症状消失快,CRP、血淀粉酶、血脂肪酶复常时间短.

Traditional Chinese Medicine Syndrome Differentiation Combined with Routine Western Medicine Therapy in Treatment of Acute Pancreatitis

Objective: To observe clinical efficacy of the treatment based on syndrome differentiation of traditional Chinese medicine combined with western medicine on conventional therapy for acute pancreatitis (AP). Method: With in 80 cases of AP patients were randomly divided into the observation group and the control group (40 cases in each group). Two groups of patients were monitered with fasting, gastrointestinal decompression, correcting water and electrolyte disturbances, regulating acid-base balance; inhibiting gastric acid secretion and pancreatin, resisting infection, symptomatic treatment of spasmodic pain. Observation group was treated on the basis of traditional Chinese medicine with treatment based on syndrome differentiation, 1/d decoction of 2-3 times the oral or nasal feeding. The 2 group were treated 7 d for 1 courses. Result: The cure rate was 55% in observ ation group 42.50% in control group , two groups had significant difference (P<0.05); the total efficiency was 92.50% in observation group, 77.50% in the control group, two groups had significant difference (P<0.05). Abdominal distention, abdominal pain, fever, constipation and other clinical symptoms disappeared time were (3.08±1.83), (2.33±1.22), (2.54±1.67), (1.18±0.42) d in observation group,(5.14±1.78), (4.57± 1.30), (6.93±1.88), (3.22±0.85) d in control group respectively.The observation group was better than control group (P<0.05). CRP, blood amylase, serum lipase recovery time, hospitalization time were (6.11± 1.53), (4.48±1.86), (4.64±1.64), (8.53±2.42) d in observation group,(9.56±2.68), (8.63±1.98), (7.05±1.84), (13.48±3.67) d in control group respectively. The observation group was beeter than control group (P<0.05 ). Conclusion: The efficacy of traditional Chinese medicine syndrome differentiation combined with western medicine treatment for conventional AP was significant, abdominal distension, abdominal pain, fever, constipation and other clinical symptoms disappeared, CRP, blood amylase, serum lipase recovery time was shortemed.