| 血流能量图及微血管密度与乳腺癌腋窝淋巴结转移的相关性 |
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| 引用本文： | 李逢生,刘文虹,袁权,宋张骏,朱江,郭亮,袁勇,张秉亨.血流能量图及微血管密度与乳腺癌腋窝淋巴结转移的相关性[J].现代肿瘤医学,2011,19(10):2001-2004. |
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| 作者姓名： | 李逢生 刘文虹 袁权 宋张骏 朱江 郭亮 袁勇 张秉亨 |
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| 作者单位： | 1. 陕西省肿瘤医院,陕西,西安,710061
2. 西安交通大学第二附属医院超声科,陕西,西安,710004 |
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| 摘 要： | 目的:探讨血流能量图angio(Power Doppler Imaging,PDI)及微血管密度(microvessel density,MVD)与乳腺癌腋淋巴转移的相关性。方法:术前观察74例乳腺癌的血流信号及血流能量图特征;术后标本采用免疫组化检测癌巢内MVD值,比较PDI与MVD两种方法与乳腺癌腋淋巴结转移的关系。结果:43个有腋淋巴结转移(LN+)组肿块以Ⅱ、Ⅲ级血流为主,血流主要分布在肿块周边多呈"爪"分布,血流信号较无腋淋巴结转移(LN-)组31个肿块明显丰富(P<0.05)。LN+组MVD值>LN-组(P<0.05)。癌巢内MVD值随Adler血流分级的增高和肿块体积的增大而测值增高(P<0.05),且随组织学级别的增加而显著增大(P<0.05)。结论:乳腺癌的PDI及MVD值与腋淋巴结转移密切相关,二者结合可作为评估乳腺癌患者预后的重要指标。
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| 关 键 词： | 血流能量图 微血管密度 免疫组织化学 淋巴结转移 |
Correlations between microvessel density and angio with axillary lymph node metastasis in patients with primary breast carcinoma |
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| LI Fengsheng,LIU Wenhong,YUAN Quan,SONG Zhangjun,ZHU Jiang,GUO Liang,YUAN Yong,ZHANG Bingheng.Correlations between microvessel density and angio with axillary lymph node metastasis in patients with primary breast carcinoma[J].Journal of Modern Oncology,2011,19(10):2001-2004. |
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| Authors: | LI Fengsheng LIU Wenhong YUAN Quan SONG Zhangjun ZHU Jiang GUO Liang YUAN Yong ZHANG Bingheng |
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| Institution: | LI Fengsheng1,LIU Wenhong1,YUAN Quan1,SONG Zhangjun1,ZHU Jiang1,GUO Liang1,YUAN Yong1,ZHANG Bingheng2 1Shaanxi Cancer Hospital,Shaanxi Xi'an 710061,China,2Second Affiliate Hospital of Medical Colledge of Xi'an Jiaotong University,Shaanxi Xi'an 710004,China. |
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| Abstract: | Objective:To explore the correlation between angiogenesis and axillary lymphnode metastasis in primary breast carcinoma.Methods: All 74 patients underwent Power Doppler Imaging(PDI)for categorizing the blood grades before operation.Microvessel density(MVD)was immunohistologically stained and measured with CD34 and VEGF.Axillary lymphnode metastasis was examined in pathology specimens.Results: Blood signal grade was between 2 and 3 in the 43 LN+,blood flow was mainly distributed in the mass surrounding as a ... |
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| Keywords: | Power Doppler Imaging(PDI) microvessel density(MVD) immnuohistochemical lymphnode metastasis |
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