| 中药联合放疗对中晚期食管癌患者T细胞亚群和IL-2表达的影响 |
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| 引用本文： | 苏丽,夏黎明,李平,张梅.中药联合放疗对中晚期食管癌患者T细胞亚群和IL-2表达的影响[J].现代肿瘤医学,2011,19(10):1988-1989. |
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| 作者姓名： | 苏丽 夏黎明 李平 张梅 |
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| 作者单位： | 1. 安徽省立医院中医科,安徽,合肥,230001
2. 安徽省中医院肿瘤科,安徽,合肥,230038 |
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| 基金项目： | 安徽省教育厅自然科学重点资助项目 |
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| 摘 要： | 目的:探讨中药联合放疗对中晚期食管癌患者T细胞亚群和IL-2表达的影响。方法:将40例患者随机分为对照组(单纯放疗)20例、治疗组(中药复方守宫散联合放疗)20例。分别采用单克隆抗体碱性磷酸酶法、ELISA放射免疫分析法对两组患者的T细胞亚群和IL-2进行检测。结果:治疗组在治疗后CD4+、CD4+/CD8+均较治疗前有显著提高(P<0.05),治疗后CD8+水平较治疗前有明显下降(P<0.05)。对照组在治疗后CD4+、CD4+/CD8+均较治疗前有明显下降(P<0.05),而CD8+在治疗后较治疗前有显著提高(P<0.05)。治疗组治疗后改细胞亚群改善情况明显优于对照组(P<0.05);治疗组治疗后IL-2表达较治疗前有显著提高(P<0.05),对照组治疗后IL-2表达较治疗前无明显差异(P>0.05),治疗组治疗后IL-2表达明显高于对照组(P<0.05)。结论:复方守宫散不仅可调节、提高中晚期食管癌放疗患者的免疫功能,亦可减轻放疗对机体免疫功能的损害。
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| 关 键 词： | 中药 放疗 中晚期食管癌 T细胞亚群 IL-2 |
The effect of Chinese medicine adjuvant radiotherapy on the expression of T lymphocyte subsets and IL - 2 in advanced esophageal cancer patients |
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| SU Li,XIA Liming,LI Ping,ZHANG Mei.The effect of Chinese medicine adjuvant radiotherapy on the expression of T lymphocyte subsets and IL - 2 in advanced esophageal cancer patients[J].Journal of Modern Oncology,2011,19(10):1988-1989. |
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| Authors: | SU Li XIA Liming LI Ping ZHANG Mei |
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| Institution: | SU Li1,XIA Liming2,LI Ping1,ZHANG Mei1 1Anhui Provincial Hospital,Hefei 230001,China,2Anhui College of Traditional Chinese Medicine,Hefei 230038,China. |
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| Abstract: | Objective:To investigate the effect of Chinese medicine adjuvant radiotherapy on the expression of T lymphocyte subsets and IL-2 in the medium-term or advanced esophageal caner. Methods: All 40 patients of medium-term or advanced esophageal cancer were randomly divided into 20 cases of the control group (Pure radiotherapy) and 20 cases of the treatment group (Fufang Shougong San adjuvant radiotherapy).To detect the expression of T lymphocyte subsets and IL-2 by using monoclonal antibody alkaline phosphoric ... |
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| Keywords: | Chinese medicine radiotherapy advanced esophageal cancer T lymphocyte subsets IL - 2 |
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