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Phosphatidylcholine content and fatty acid composition of tracheal and gastric liquids from premature and fullterm newborn infants |
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| Authors: | Etsuro K. Motoyama Yoshimichi Namba Seamus A. Rooney |
| Affiliation: | Departments of Anesthesiology and Pediatrics and Lung Research Center, Yale University School of Medicine, 333 Cedar Street, New Haven, Conn. 06510, U.S.A. |
| Abstract: | The phosphatidylcholine content and fatty acid composition of tracheal and gastric liquids from newborn full-term and premature (30–36 weeks) infants were studied. Phosphatidylcholine accounted for about 70% of the total phospholipids in both liquids from the full-term infants but only 55–57% of those from the prematures. There was a significant correlation between tracheal and gastric liquids in the fatty acid composition of phosphatidylcholine. There were significant differences in fatty acid composition between the full-term and premature liquids. These differences were most apparent in the gastric liquid. It is suggested that phospholipid or fatty acid analysis of tracheal or gastric liquids from newborn infants can be used in the assessment of pulmonary maturity. |
| Keywords: | Address for correspondence: Dr. Seamus A. Rooney Department of Pediatrics Yale University School of Medicine 333 Cedar Street New Haven Conn. 06510 U.S.A. |
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