Impact of the COVID-19 pandemic on routine immunization coverage in children under 2 years old in Ontario,Canada: A retrospective cohort study |
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| Institution: | 1. Department of Family and Community Medicine, University of Toronto, 500 University Avenue, 5th Floor, Toronto, Ontario M5G 1V7, Canada;2. Toronto Western Family Health Team, University Health Network, 440 Bathurst Street, 3rd Floor, Toronto, Ontario M5T 2S6, Canada;3. Division of Infectious Diseases, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada;4. Department of Paediatrics, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada, M5G 1X8;5. Mount Sinai Academic Family Health Team, 60 Murray Street, 4th Floor, Toronto, Ontario M5T 3L9, Canada;6. Division of Paediatric Medicine, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada;7. Centre for Global Child Health and the SickKids Research Institute, Peter Gilgan Centre for Research and Learning, 686 Bay Street, 11th Floor, Suite 11.9805, Toronto, Ontario M5G 0A4, Canada;8. Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Ontario M5T 3M7, Canada;9. North York General Hospital, 4001 Leslie Street, Toronto, Ontario M2K 1E1, Canada |
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| Abstract: | BackgroundThe COVID-19 pandemic has caused a disruption in childhood immunization coverage around the world. This study aimed to determine the change in immunization coverage for children under 2 years old in Ontario, Canada, comparing time periods pre-pandemic to during the first year of the pandemic.MethodsObservational retrospective open cohort study, using primary care electronic medical record data from the University of Toronto Practice-Based Research Network (UTOPIAN) database, from January 2019 to December 2020. Children under 2 years old who had at least 2 visits recorded in UTOPIAN were included. We measured up-to-date (UTD) immunization coverage rates, overall and by type of vaccine (DTaP-IPV-Hib, PCV13, Rota, Men-C-C, MMR, Var), and on-time immunization coverage rates by age milestone (2, 4, 6, 12, 15, 18 months). We compared average coverage rates over 3 periods of time: January 2019-March 2020 (T1); March-July 2020 (T2); and August-December 2020 (T3).Results12,313 children were included. Overall UTD coverage for all children was 71.0% in T1, dropped by 5.7% (95% CI: ?6.2, ?5.1) in T2, slightly increased in T3 but remained lower than in T1. MMR vaccine UTD coverage slightly decreased in T2 and T3 by approximately 2%. The largest decreases were seen at ages 15-month and 18-month old, with drops in on-time coverage of 14.7% (95% CI: ?18.7, ?10.6) and 16.4% (95% CI: ?20.0, ?12.8) respectively during T2. When stratified by sociodemographic characteristics, no specific subgroup of children was found to have been differentially impacted by the pandemic.ConclusionChildhood immunization coverage rates for children under 2 years in Ontario decreased significantly during the early period of the COVID-19 pandemic and only partially recovered during the rest of 2020. Public health and educational interventions for providers and parents are needed to ensure adequate catch-up of delayed/missed immunizations to prevent potential outbreaks of vaccine-preventable diseases. |
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| Keywords: | Immunization coverage Childhood immunization COVID-19 Primary care Family medicine Pediatrics Health services Retrospective observational study EMR"} {"#name":"keyword" "$":{"id":"k0050"} "$$":[{"#name":"text" "_":"Electronic Medical Records GTA"} {"#name":"keyword" "$":{"id":"k0060"} "$$":[{"#name":"text" "_":"Greater Toronto Area SES"} {"#name":"keyword" "$":{"id":"k0070"} "$$":[{"#name":"text" "_":"Socioeconomic Status UTOPIAN"} {"#name":"keyword" "$":{"id":"k0080"} "$$":[{"#name":"text" "_":"University of Toronto Practice-Based Research Network VPDs"} {"#name":"keyword" "$":{"id":"k0090"} "$$":[{"#name":"text" "_":"Vaccine Preventable Diseases |
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