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The gut microbiome,mild cognitive impairment,and probiotics: A randomized clinical trial in middle-aged and older adults |
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| Institution: | 1. Center for Gastrointestinal Biology and Disease (CGIBD), Department of Medicine, Division of Gastroenterology and Hepatology, School of Medicine, UNC Microbiome Core, University of North Carolina, Chapel Hill, NC, USA;2. Department of Plant and Microbial Biology, North Carolina State University, Raleigh, NC, USA;3. Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia;4. Department of Psychological Sciences, Kent State University, USA;5. Department of Medicine, School of Medicine, Brain Health Research Institute, Kent State University, USA;1. Brain Plasticity Group, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, the Netherlands;2. Amsterdam UMC, University of Amsterdam, Vrije Universiteit, Emma Children''s Hospital, Amsterdam Reproduction and Development Institute, Amsterdam, the Netherlands;3. Danone Nutricia Research, Utrecht, the Netherlands;4. Amsterdam UMC, University of Amsterdam, Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands;1. Μedical Research Council Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, United Kingdom;2. Public Health Policy Evaluation Unit, Imperial College London, London W6 8RP, United Kingdom;3. Department of Nutrition, School of Public Health, University of São Paulo, São Paulo 01246-904, Brazil;4. Center for Epidemiological Research in Nutrition and Health, School of Public Health, University of São Paulo, São Paulo 01246-904, Brazil;5. Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, MA, U. S. A;6. Centre for Health Economics & Policy Innovation, Department of Economics & Public Policy, Imperial College Business School, South Kensington Campus, London, United Kingdom;7. Comprehensive Health Research Center and Public Health Research Centre, National School of Public Health, NOVA University Lisbon, Portugal;8. Mohn Centre for Children''s Health and Well-being, School of Public Health, Imperial College London, United Kingdom;1. School of Kinesiology & Nutrition, College of Education and Human Sciences, University of Southern Mississippi, Hattiesburg, MS 39406, USA;2. Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX 79409, USA |
| Abstract: | 
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| Keywords: | Gut microbiome Cogitative aging Psychobiotics MCI"} {"#name":"keyword" "$":{"id":"kwrd0040"} "$$":[{"#name":"text" "_":"mild cognitive impairment LGG"} {"#name":"keyword" "$":{"id":"kwrd0050"} "$$":[{"#name":"text" "$$":[{"#name":"italic" "_":"Lactobacillus rhamnosus"} {"#name":"__text__" "_":" GG AD"} {"#name":"keyword" "$":{"id":"kwrd0060"} "$$":[{"#name":"text" "_":"Alzheimer's disease PD"} {"#name":"keyword" "$":{"id":"kwrd0070"} "$$":[{"#name":"text" "_":"Parkinson's disease IL-8"} {"#name":"keyword" "$":{"id":"kwrd0080"} "$$":[{"#name":"text" "_":"interleukin-8 OCD"} {"#name":"keyword" "$":{"id":"kwrd0090"} "$$":[{"#name":"text" "_":"obsessive-compulsive disorder WGS"} {"#name":"keyword" "$":{"id":"kwrd0100"} "$$":[{"#name":"text" "_":"whole-genome shotgun GlnRS"} {"#name":"keyword" "$":{"id":"kwrd0110"} "$$":[{"#name":"text" "_":"glutaminyl-tRNA synthetase SIA"} {"#name":"keyword" "$":{"id":"kwrd0120"} "$$":[{"#name":"text" "_":"species indicator analysis PCoA"} {"#name":"keyword" "$":{"id":"kwrd0130"} "$$":[{"#name":"text" "_":"principal coordinate analysis PICRUSt"} {"#name":"keyword" "$":{"id":"kwrd0140"} "$$":[{"#name":"text" "_":"phylogenetic investigation of communities by reconstruction of unobserved states ZIBR"} {"#name":"keyword" "$":{"id":"kwrd0150"} "$$":[{"#name":"text" "_":"zero-inflated beta regression model with random effects RCT"} {"#name":"keyword" "$":{"id":"kwrd0160"} "$$":[{"#name":"text" "_":"randomized clinical trials MDD"} {"#name":"keyword" "$":{"id":"kwrd0170"} "$$":[{"#name":"text" "_":"major depressive disorder BPD"} {"#name":"keyword" "$":{"id":"kwrd0180"} "$$":[{"#name":"text" "_":"bipolar disorder with current major depressive episodes MHE"} {"#name":"keyword" "$":{"id":"kwrd0190"} "$$":[{"#name":"text" "_":"minimal hepatic encephalopathy HD"} {"#name":"keyword" "$":{"id":"kwrd0200"} "$$":[{"#name":"text" "_":"Huntington's disease GABA"} {"#name":"keyword" "$":{"id":"kwrd0210"} "$$":[{"#name":"text" "_":"gamma-aminobutyric acid SCFAs"} {"#name":"keyword" "$":{"id":"kwrd0220"} "$$":[{"#name":"text" "_":"Short-chain fatty acids POCD"} {"#name":"keyword" "$":{"id":"kwrd0230"} "$$":[{"#name":"text" "_":"postoperative cognitive dysfunction ASD"} {"#name":"keyword" "$":{"id":"kwrd0240"} "$$":[{"#name":"text" "_":"autism spectrum disorders MIND"} {"#name":"keyword" "$":{"id":"kwrd0250"} "$$":[{"#name":"text" "_":"mediterranean-DASH intervention for neurodegenerative delay TSS"} {"#name":"keyword" "$":{"id":"kwrd0260"} "$$":[{"#name":"text" "_":"total sum scaling CLR"} {"#name":"keyword" "$":{"id":"kwrd0270"} "$$":[{"#name":"text" "_":"centered log-ratio LEfSe"} {"#name":"keyword" "$":{"id":"kwrd0280"} "$$":[{"#name":"text" "_":"linear discriminant analysis LDA and effect size |
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