XStrainTM技术评价尿毒症患者左心室局部与整体收缩功能

目的 探讨XStrain^TM技术测定尿毒症心肌病患者左心室局部与整体收缩功能的可行性。方法 将28例尿毒症患者分两组,A组左心室非肥厚12例,B组左心室肥厚16例;C组为正常对照16名。经胸超声心动图采集并存储3个心动周期心尖四腔心、两腔心及三腔心切面二维灰阶图像。采用XStrain^TM定量软件进行脱机分析,获得收缩期左心室壁16节段纵向/横向应变及应变率,对16节段应变参数取平均值获得整体纵向/横向应变数据,并对以上参数进行统计学分析。结果 16节段心肌收缩期纵向应变及应变率(除中间段后间隔外)、横向应变(除中间段前间壁和后间壁外)、横向应变率为C组>A组>B组(P均<0.05)。尿毒症患者左心室收缩期整体纵向及横向应变较C组明显减低(P<0.05)。结论 XStrain^TM技术可清晰显示左心室心肌,评估左心室收缩功能,可用于定量评估尿毒症心肌病患者左心室局部与整体收缩功能。

XStrainTM echocardiography evaluation of regional and global left ventricular systolic function in uremia patients

Objective To explore the feasibility of XStrain^TM in evaluating regional and global systolic function of left ventricle (LV) in uremic cardiomyopathy patients. Methods A total of 28 uremic patients (group A, normal LV, n=12; group B, LV hypertrophy, n=16) and 16 normal subjects (group C) were enrolled. The dynamic images of apical four chamber view, apical long axis view and two chamber view by thoracic echocardiography were obtained and stored. The original data was recorded and analyzed by using a novel off-line XStrain^TM analysis software. The longitudinal/transversal systolic strain and strain rate in 16 segments were acquired. Global strains were calculated by averaging segmental strains. The statistical analysis was performed. Results Compared with group C, the longitudinal systolic strains and strain rates except for posterior septal of mid segments, the transversal systolic strains except for anteroseptal and posteroseptal wall of mid segments, the transversal systolic strain rates were lower in all segments, which in group B were also lower than those of group A (all P<0.05). Compared with group C, the global longitudinal and transversal systolic strains were lower (all P<0.05). Conclusion XStrain^TM can display clearly and comprehensively LV myocardium, evaluate the LV systolic function, and quantitatively assess the regional and global systolic function in uremic patients.