| Abstract: | Absorption and agglutination inhibition studies carried out on human sera with intact red blood cells, secretory substances and soluble red blood cell membrane extracts show that antibodies against sheep red blood cells possess at least two types of specificities. The agglutinating type has specificities in common with human anti-A and anti-B, while the hemolytic antibody does not. Comparative titration studies clearly demonstrate that there is no correlation in the distribution of these two varieties of sheep red blood cell antibodies. Guinea pig and rat erythrocytes share human A- and B-like determinants with sheep red blood cells. Rabbit, horse and goose red blood cells do not possess these blood group factors. |
