REACTIVE ARTHRITIS: UROGENTTAL SWAB CULTURE IS THE ONLY USEFUL DIAGNOSTIC METHOD FOR THE DETECTION OF THE ARTHRITOGENIC INFECTION IN EXTRA-ARTICULARLY ASYMPTOMATIC PATIENTS WITH UNDIFFERENTIATED OLIGOARTHRITIS |
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Authors: | ERLACHER L; WINTERSBERGER W; MENSCHIK M; BENKE-STUDNICKA A; MACHOLD K; STANEK G; SOLTZ-SZOTS J; SMOLEN J; GRANINGER W |
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Institution: | Department of Internal Medicine III, Division of Rheumatology, University of Vienna Vienna, Austria
*Department of Microbiology, University of Vienna Vienna, Austria
Department of Dermatology, University of Vienna Vienna, Austria |
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Abstract: | Reactive arthritis (ReA) is a scronegative oligoarthritis triggeredby a preceding extra-articular infection. While evidence ofa microbial infection is mandatory for establishing the diagnosisof ReA, the sensitivity of bacteriological and serological testshas not been determined in patients without symptoms of infection.In a retrospective study, we evaluated the usefulness of urogenitalswab cultures, serology and stool culture to identify infectionsin 234 patients with undifferentiated oligoarthritis. One hundredand forty-four patients complaining about joint pain who hadno sign or history of inflammatory arthritis served as controls.Urogenital swab cultures showed a microbial infection in 44%of the patients with oligoarthritis (15% Chlamydia, 14% Mycoplasma,28% Ureaplasma), whereas in the control group only 26% had apositive result (4% Chlamydia, 7% Mycoplasma, 21% Ureaplasma)(P < 0.001). A Chlamydia IgG-antibody titre |
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