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尼卡地平治疗心绞痛
引用本文:黄震华,徐济民. 尼卡地平治疗心绞痛[J]. 中国新药与临床杂志, 1994, 0(3)
作者姓名:黄震华  徐济民
作者单位:上海第二医科大学附属第九人民医院心血管病研究室
摘    要:冠心病心绞痛74例,其中46例(男性32例,女性14例;年龄65±s8a)采用尼卡地平40mg,po,bid为治疗组;另28例(男性15例,女性13例;年龄62±9a)采用丹参舒心胶囊2粒,po,tid为对照组。12wk后,临床与心电图总有效率,治疗组依次为91%和72%,对照组为68%和43%,治疗组优于对照组(P均<0.001)。尼卡地平尚有减慢心率。降低血压及改善左室收缩功能等作用,不良反应轻微。

关 键 词:尼卡地平,丹参,心绞痛

Nicardipine in the treatment of angina pectoris
HUANG Zhen-Hua,XU Ji-Min. Nicardipine in the treatment of angina pectoris[J]. Chinese Journal of New Drugs and Clinical Remedies, 1994, 0(3)
Authors:HUANG Zhen-Hua  XU Ji-Min
Abstract:Forty six patients(M32,F14;age 65±s 8 a)with angina pectoris were treated with nicardipine(40 mg,po,bid×12 WK).The clinical total effective rate was 91%and ECG total effective rate was 72%.Another 28 patients(M 15,F13;age 62±9 a) were treate d with Dan-shen-shu-xing capsule 2 pills(each pill contains Salvia miltiorrhiza 0.2g)po,tid×12 WK.The clinical total effective rates were 68% and 43% respectively.Nicardipine group were superior than Salvia miltiorrhiza group(P<0.001).Nicardipine slowd herat rate,decreaed blood pressure,and improved the svstolic function of left ventricle.Adverse reactions were mild.
Keywords:nicardipine  Salvia miltiorrhiza  angina pectoris  
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