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骨肉瘤保肢重建术式与患者预后
引用本文:吴兴,陈峥嵘,张光健. 骨肉瘤保肢重建术式与患者预后[J]. 中国矫形外科杂志, 2003, 11(23): 1594-1596
作者姓名:吴兴  陈峥嵘  张光健
作者单位:复旦大学附属中山医院骨科,上海,200032
摘    要:目的:评价骨肉瘤保肢手术重建方法与患者的远期预后的关系。方法:回顾性研究1985~1999年50例行保肢手术的IIB期肢体骨肉瘤患者。重建方法:灭活再植25例,肿瘤型人工假体置换12例,异体半关节置换9例,带血管腓骨移植4例。统计学分析不同重建方法与患者远期预后的关系。结果:保肢手术中非瘤段保留组患者较瘤段保留组患者局部复发率低,远期生存率高;有统计学差异。结论:骨肉瘤保肢术应首选人工关节置换、异体骨移植等非瘤骨保留型重建手术。

关 键 词:骨肉瘤 保肢重建术 肿瘤 手术 治疗 临床资料
文章编号:1005-8478(2003)23-1594-03
修稿时间:2003-05-23

Reconstruction Surgery of Osteosarcoma and Prognosis of Patients
WU Xing,CHEN Zheng rong,ZHANG Guang jian. Reconstruction Surgery of Osteosarcoma and Prognosis of Patients[J]. The Orthopedic Journal of China, 2003, 11(23): 1594-1596
Authors:WU Xing  CHEN Zheng rong  ZHANG Guang jian
Affiliation:WU Xing,CHEN Zheng rong,ZHANG Guang jian. Department of Orthopaedics,Zhongshan Hospital,Fudan University,Shanghai 200032
Abstract:Objective: To evaluate the relation between various reconstruction surgeries in primary osteosarcoma cases and prognosis of patients. Methods: Between 1985 and 1999, 50 patients aging from 11 to 55 years with the diagnosis of II B extremity osteosarcoma, were treated with definitive surgery and adjuvant chemotherapy regimens, which included devitalized tumor bone reimplantation in 25 cases, endoprosthestic replacement in 12 cases, osteoarticular allograft implantation in 9 cases, and vascularized fibula autograft implantation in 4 cases. Result: The long-term prognosis of patients in tumor bone reservation group was worse than those in tumor bone non-reservation group. Conclusion: Endoprosthestic replacement is the best choice of limb salvage surgery in osteosarcoma cases.
Keywords:Osteosarcoma  Limb salvage surgery  Reconstruction operation
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