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Influences of ERCC1, ERCC2, XRCC1, GSTP1, GSTT1, and MTHFR polymorphisms on clinical outcomes in gastric cancer patients treated with EOF chemotherapy |
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| Authors: | Liu Rujiao Zhao Xiaoying Liu Xin Chen Zhiyu Qiu Lixin Geng Ruixuan Guo Weijian He Guang Yin Jiliang Li Jin Zhu Xiaodong |
| Affiliation: | 1.Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China ;2.Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong’An Road, Shanghai, 200032, People’s Republic of China ;3.Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai, 200030, China ;4.Institute for Nutritional Sciences, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, China ; |
| Abstract: | Tumor Biology - This study investigated the associations between genetic polymorphisms of six genes involved in DNA repair, detoxification pathways, and fluoropyrimidine metabolism and clinical... |
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