Simultaneous papillary carcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma of the thyroid; a case report |
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| Institution: | 1. Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy;2. Institute of Hematology, Catholic University, Rome;3. IRCCS Fondazione Policlinico San Matteo, Pavia, Italy;4. Department of Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy;5. Department of Hematology, Ospedale S. Giovanni Bosco, Turin, Italy;6. Department of Internal Medicine, Ospedale S. Martino, Genoa, Italy;7. Hemophilia and Thrombosis Center, Department of Hematology, Azienda Ospedaliera \"Pugliese-Ciaccio\", Catanzaro, Italy;8. Centro Trombosi, S.C. Medicina Interna, Ospedale Galliera, Genoa, Italy;9. Thrombosis Center, Ospedale Careggi, Florence, Italy;10. A. Bianchi Bonomi Hemophilia and Thrombosis Center, Department of Internal Medicine and Medical Specialties, Fondazione IRCCS Ca'' Granda - Ospedale Maggiore Policlinico, Milan, Italy;11. U.O. di Ematologia con trapianto, Dipartimento Biomedico di Medicina Interna e Specialistica, University of Palermo, Italy;12. Department of Transfusional Medicine, Ospedale S. Maria della Misericordia, Udine, Italy;13. Medicina 3, Ospedale S.Paolo and Dipartimento di Scienze della Salute, University of Milan, Italy;14. Clinica Medica, Azienda Ospedaliero Universitaria, Sassari, Italy;15. U.O.C Ematologia e Centro Trapianti, A.O. San Gerardo di Monza, Italy;p. Department of Hematology, Ospedale S. Bortolo, Vicenza, Italy |
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| Abstract: | Primary lymphoma of the thyroid is an uncommon malignancy, whereas papillary thyroid carcinoma is the most common thyroid malignancy. Both have an association with Hashimoto's thyroiditis. We discuss a case of an 83 year old male who presented with a large neck swelling, which subsequently proved to be a primary thyroid lymphoma (extra-nodal marginal zone) with concurrent papillary thyroid carcinoma. These tumours manifested on a background of Hashimoto's thyroiditis. To date there have only been 13 other cases of joint papillary thyroid carcinoma and thyroid lymphoma within the literature. Our case report adds to this by discussing diagnosis, histopathological features and pitfalls in early detection. |
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| Keywords: | autoimmune thyroiditis Hashimoto's thyroiditis MALT lymphoma papillary thyroid carcinoma thyroid |
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