| 亚临床甲状腺功能减退症与动脉粥样硬化的关系分析 |
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| 引用本文： | 李博一,文磊,罗平,张健伟. 亚临床甲状腺功能减退症与动脉粥样硬化的关系分析[J]. 医学理论与实践, 2012, 25(9): 1022-1023,1025 |
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| 作者姓名： | 李博一 文磊 罗平 张健伟 |
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| 作者单位： | 云南省昆明市第一人民医院内分泌科,650011 |
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| 摘 要： | 目的:对亚临床甲状腺功能减退症与动脉粥样硬化的关系进行探讨。方法:123例患者根据甲状腺功能分为正常对照组40例,亚临床甲状腺功能减退症组45例,临床甲状腺功能减退症组38例,分别对其血脂,超敏C反应蛋白(CRP),颈动脉内膜中层厚度(IMT)进行比较。结果:亚临床甲状腺功能减退症组的胆固醇(TC)、低密度脂蛋白(LDL-C)明显高于对照组(P<0.05),且与临床甲状腺功能减退症组之间无显著性差异(P>0.05);亚临床甲状腺功能减退症组、临床甲状腺功能减退症组CRP、IMT高于对照组(P<0.05)且临床甲状腺功能减退症组高于亚临床甲状腺功能减退症组(P<0.05)。结论:亚临床甲状腺功能减退症引起并加速动脉粥样硬化,是动脉粥样硬化的独立危险因素。
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| 关 键 词： | 亚临床甲状腺功能减退症 动脉粥样硬化 |
Analysis of the Relations Between Subclinical Thyroid Gland Hypofunction and Atherosclerosis |
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| Affiliation: | LI Boyi,WEN Lei,LUO Ping,et al.Department of Endocrinology,The First People’s Hospital of Kunming City,Yunnan Province 650011 |
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| Abstract: | Objective:Analysis of the relations between subclinical thyroid gland hypofunction and atherosclerosis.Methods:The 123 patients are divided into:the control group of 40 cases,the subclinical thyroid gland hypofunction group of 45 cases and the clinical thyroid gland hypofunction group of 38 cases;these three groups will be studied by terms of blood fat,(H)CRP(hypersensitive creative protein) and IMT respectively.Results:TC and LDL-C shown in the subclinical thyroid gland hypofunction group are significantly higher than the control group(P<0.05),but is not remarkably different from the clinical thyroid gland hypofunction group(P>0.05);while CRP and IMT tested in both the subclinical thyroid gland hypofunction group and the clinical thyroid gland hypofunction group are higher than the control group(P<0.05).Conclusion:Subclinical thyroid gland hypofunction which triggers and expedites atherosclerosis is an independent risk factor of atherosclerosis. |
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| Keywords: | Subclinical thyroid gland hypofunction Atherosclerosis |
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