92例重度子痫前期临床观察

目的:探讨重度子痫前期相关的临床特点。方法:随机选择重度子痫前期患者92例。观察组:小于34周发病的孕妇46例。对照组:大于等于34周发病的孕妇46例。两组病例均为单个胎儿妊娠,年龄、体重无显著性差异。最大年龄为41.5岁,最小年龄为21.6岁,平均年龄为30.6岁。发病的孕周最大者为41周,最小者为28周,平均发病孕周为34.5周。诊断标准符合文献所载。入院时监测血压、谷丙转氨酶、血肌酐、24h尿蛋白。动态监测血压,采取硫酸镁解痉降低血压、使用各类降压药物,保护肝脏、肾脏等综合治疗,对比两组入院时相关指标、孕妇相关并发症、围生儿结局。所有数据以均数±标准差(x珚±s)表示,P<0.05。结果:入院时相关指标观察组明显高于对照组,孕妇、围生儿的相关并发症观察组也明显高于对照组。小孕周罹患早发型重度子痫前期者,并发症多、病情重。P<0.05。结论:重度子痫前期妊娠结局与罹患该病的孕周相关,小孕周即罹患早发型重度子痫前期者结局不良。

92 severe preeclampsia cases Clinical observation

Objective：To investigate the clinical features of severe preeclampsia related. Methods：random selection patients with severe preeclampsia 92 cases. The observation group： gestational age less than 34 weeks pregnant women, 46 cases. Control group： greater than or equal to 34 weeks pregnant women, 46 cases. Two groups cases are single fetal pregnancy. There was no significant difference in age, body weight. The maximum age 41.5 years, the minimum age 21.6 years, the average age is 30.6 years old. The pathogenesis of gestational weeks maximum for 41 weeks, the minimum for 28 weeks, the average gestational age is 34.5 weeks. Diagnostic criteria in line with the literature contained. At the time of admission monitoring blood pressure, Alanine aminotransferase, serum ereatinine, 24 hours urine protein. Dynamic monitoring of blood pressure, taking magnesium sulfate treatment, using various types of antihypertensive drugs to lower blood pressure, protect the liver, kidney and other comprehensive treatment, corn pared two groups at admission associated index, pregnant complications, perinatal outcome. All data to mean SD （x- ±s）, P〈0.05. Results：admission related indexes of the observation group were higher than the control group, maternal, perinatai complications related to the observation group were significantly higher than those in control group. Small gestational week with early onset of severe preeclampsia, more complications, severe illness. P〈0.05. Conclusion：severe pre-eclampsia pregnancy outcome and risk of the disease in the gestational weeks, small gestational weeks that risk of early onset severe preeclampsia are adverse outcomes.