氟西汀对急性缺血性脑卒中患者运动功能的影响

目的 探讨氟西汀改善急性缺血性脑卒中患者肢体运动功能的作用.方法 急性缺血性脑卒中患者60例,随机分成氟西汀组和对照组,对照组予常规药物治疗和康复治疗,氟西汀组加用氟西汀20 mg qd po,分别在给药前、给药后30 d、给药后90 d进行FMMS评分,评价2组运动功能情况.结果 发现在给药后90 d,氟西汀组FMMS评分明显高于对照组,2组比较差异有统计学意义（P＜0.05）.结论 对于以运动功能障碍为主要表现的急性缺血性脑卒中患者,早期给予小剂量氟西汀口服（20 mg/d）并配合物理疗法,对患者的运动功能恢复有一定帮助.

Effect of fluoxetine on motor function of the patients with acute ischemic stroke

Objective To explore the effect of fluoxetine on improving the motor function of the patients with acute ische- mic stroke. Methods Sixty acute ischemic stroke patients were randomly divided into two groups- fluoxetine group and control group, fiuoxetine group received fluoxetine 20 mg qd po , besides routine medicine treatment and rehabilitation training, and FMMS were used to evaluate the motor function of patients before the treatment, on the 30 day and the 90 day after the treat- ment of fluoxetine. Results There were significant difference on the 90 day in FMMS between the fluoxetine group and control group （P〈0.05）. Conclusion For patients with acute isehemie stroke whose motor dysfunction is main symptom, fl low dose of uoxetine intake（20 mg/d） combined with physical therapy, can help their motor function recovery.