急性脑血管病并发癫（癎）的临床研究

目的 研究急性脑血管病并发癫（癎）的发病机制、疾病特征、治疗与预后.方法 选取2008-01-2011-12我院862例急性脑血管病患者,其中并发癫（癎）患者73例,给予正规原发疾病的治疗以及相应抗癫（癎）治疗,比较分析急性脑血管病并发癫（癎）的发病率、发作类型、发作时间、病死率等.结果 急性脑血管病并发癫（癎）的发病率为8.47%,其中脑梗死占8.03%（37/461）,脑出血占9.87 %（22/223）,蛛网膜下腔出血占9.86%（14/142）;单纯部分性发作病例比例最高（P〈0.05）;急性脑血管病并发癫（癎）患者中早期发作型癫（癎）比例较高;脑出血和蛛网膜下腔出血的患者更易并发早期发作型癫（癎）（P〈0.05）,而脑梗死的患者更容易并发迟发型癫（癎）（P〈0.05）;急性脑血管病并发癫（癎）患者总病死率为36.99%,明显高于未并发癫（癎）患者（P〈0.05）.结论 急性脑血管病并发癫（癎）的发病率为8.47%,以早期发作型癫（癎）比例较高,且病死率较高.

Clinical study of acute cerebrovascular disease complicated with epilepsy

Objective To study the pathogenesis of acute cerebrovascular disease complicated by epilepsy, disease charac- teristics, treatment and prognosis. Methods 862 cases of acute cerebrovascular disease, including concurrent epilepsy patiefits 73 cases, from January 2008 to December 2011 in our hospital were selected. They received the formal treatment of primarY disease and the antiepileptic treatment, and the incidence of acute cerebrovascular disease complicated by epilepsy, seizure types, onset time, and fatality rate were compared. Results the incidence of acute cerebrovascular disease complicated by epi- lepsy was 8.47%, including cerebral infarction was 8.03% （37/461）, intrcranial hemorrhage was 9.87 %（22/223）, subarach- noid hemorrhage was 9.86% （14/142） ; the highest percentage of cases was simple partial seizure （P〈 0.05） ; the proportion early onset epilepsy was significantly higher （P〈 0.05） ; Intracranial hemorrhage and subarachnoid hemorrhage patients were more likely to be complicated with early onset epilepsy （P〈0.05）, while cerebral infarction patients were more easily compli- cated with late onset epilepsy （P〈0.05）; Overall fatality rate of cute cerebrovascular disease complicated by epilepsy was 36.99% ,and was significantly higher than thar without epilepsy （P〈0.05）. Conclusion The incidence of acute cerebrovascu- lar disease complicated by epilepsy is 8.47%, percentage and fatality rate of early onset epilepsy is higher.