PROPRANOLOL IN THE SURGICAL TREATMENT OF HYPERTHYROIDISM

ＰＲＯＰＲＡＮＯＬＯＬＩＮＴＨＥＳＵＲＧＩＣＡＬＴＲＥＡＴＭＥＮＴＯＦＨＹＰＥＲＴＨＹＲＯＩＤＩＳＭＫｕａｎｇＹａｏｌｉｎ；（邝耀麟），ＳｈｅｎＹｏｕｑｉｎ；（沈又琴），ＹｉｎＺｈｉｑｉａｎｇ；（殷志强）Ａｂｓｔｒａｃｔ：ＦｒｏｍＪｕｌｙ１９７６ｔｏ...

PROPRANOLOL IN THE SURGICAL TREATMENT OF HYPERTHYROIDISM

From July 1976 to Oct. 1993, propranolol war used to prepare 154 thyrotoxic patients including 95 severe cases. The initial dose of propranolol was gradually increased to 160 mg/d and Lngol's solution war added in for 10-14 days after the pulse rate had become stable. Just before operation another dose of propranolol was given, and propranolol intake war resumed within 6-8 hours after operation. The thyrotoxic symptonis were controlled The postoperative course in 144 cases was uneventful. High fever and tachycardia developed in 7 patients with severe thyrotoxicosis and were controlled by intravenous hydrocortisone and increased dosape of propranolol. Only one case developed hypaplycemia 12 hours after operation. Our study demonstrated that propranolol combined with iodine is a safe method for preoperative treatment in hyperthyroidism. Although there was no thyroid crisis, we do not recommend propranolol alone as the routine preparation for severe thyrotoxicosis. Preparation with antithyroid drugs is the method of choice if the patient can tolerate.