| 激光焊接齿科镍铬-钴铬合金生物相容性研究 |
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| 引用本文： | 张连云,胡欣,梁锐英,李长义. 激光焊接齿科镍铬-钴铬合金生物相容性研究[J]. 天津医药, 2005, 33(12): 777-779 |
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| 作者姓名： | 张连云 胡欣 梁锐英 李长义 |
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| 作者单位： | 300070,天津医科大学口腔医院 |
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| 基金项目： | 天津市自然科学基金资助项目（项目编号：043601111） |
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| 摘 要： | 目的：评价激光焊接齿科镍铬-钴铬合金的生物相容性。方法：参照GB／T 16886技术报告相关标准，对激光焊接齿科镍铬-钴铬合金生物相容性进行体内及体外试验，包括细胞毒性试验、短期急性全身毒性试验及口腔黏膜刺激试验。结果：激光焊接齿科镍铬-钴铬合金细胞毒性实验评价级别为1级，无明显细胞毒性作用，未见任何急性毒性反应，口腔黏膜刺激试验未见异常组织学反应。结论：激光焊接齿科镍铬-钴铬合金具有良好生物相容性，安全无毒。
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| 关 键 词： | 激光 牙科合金 铬合金 生物相容性材料 |
| 收稿时间： | 2005-10-28 |
| 修稿时间： | 2005-10-282005-10-30 |
Evaluation of Biocompatibility of Laser-Welded Dissimilar Alloy in Dentistry: Co-Cr and Ni-Cr Alloy |
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| ZHANG Lianyun,HU Xin,LIANG Ruiying,LI Changyi. Evaluation of Biocompatibility of Laser-Welded Dissimilar Alloy in Dentistry: Co-Cr and Ni-Cr Alloy[J]. Tianjin Medical Journal, 2005, 33(12): 777-779 |
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| Authors: | ZHANG Lianyun HU Xin LIANG Ruiying LI Changyi |
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| Affiliation: | School of Dentistry, Tianjin Medical University, Tianjin 300070,China |
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| Abstract: | Objective: To evaluate the biological compatibility of laser-welded dissimilar alloy in dentistry: Co-Cr and Ni-Cr alloy. Methods: Cytotoxicity, acute toxicity and mucous membrane irritation were performed on the laser-welded dissimilar alloy in dentistry: Co-Cr and Ni-Cr alloy based on GB/T 16886 standard. Results: The results showed that the level of cytotoxicity was grade 1, no obrious cytotoxicity no acute toxicity and no histomorphologic changes were observed in mucous membrane. Conclusion: The laser-welded dissimilar alloy in dentistry: Co-Cr and Ni-Cr alloy has a good biocompatibility, and is safe and nonpoisonous. |
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| Keywords: | lasers dental alloys chromium alloys biocompatibility materials |
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