| 肾移植术后排斥反应与巨细胞病毒感染有关 |
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| 引用本文： | 张泓,武大林,吴涛,籍会彩. 肾移植术后排斥反应与巨细胞病毒感染有关[J]. 中国现代医学杂志, 2002, 12(2): 21-22 |
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| 作者姓名： | 张泓 武大林 吴涛 籍会彩 |
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| 作者单位： | 第一军医大学附属南方医院外科实验室,广州,510515 |
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| 摘 要： | 目的 :探讨巨细胞病毒 (CMV)感染在肾移植术后的发生率及CMV感染与排斥反应的关系。方法 :检测2 0 8例肾移植受者术后CMVDNA和 48例肾移植受者血清CMVIgM、IgG抗体。并定期复查CMVDNA ,对CMVDNA阳性的患者给予抗病毒治疗。结果 :术后CMVDNA阳性受者急性排斥反应的发生率增加 ,经抗CMV治疗 ,则排斥反应减少。结论 :预防和治疗CMV感染的重要性
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| 关 键 词： | 巨细胞病毒感染 肾移植 移植物排斥 |
| 修稿时间： | 2001-12-29 |
CYTOMEGALOVIRUS INFECTION IS RELATED TO THE REJECTION IN RENAL ALLOGRAFT RECIPIENTS |
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| Zhang Hong,Wu Dalin,Wu Tao,et al.. CYTOMEGALOVIRUS INFECTION IS RELATED TO THE REJECTION IN RENAL ALLOGRAFT RECIPIENTS[J]. China Journal of Modern Medicine, 2002, 12(2): 21-22 |
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| Authors: | Zhang Hong Wu Dalin Wu Tao et al. |
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| Affiliation: | Zhang Hong,Wu Dalin,Wu Tao,et al. The First Military Medical University,Guangzhou 510515 |
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| Abstract: | Objective:To investigate the incidence of cytomegalovirus (CMV) infection in renal allograft recipients and the impact of CMV infection on rejection.Methods:207 renal allograft recipients were subjected to the PCR for CMV DNA after transplantation,48 recipients were subjected to the serum test for CMV- antibody IgM and IgG. CMV-DNA in recipients were detected in certain time. The patients with positive CMV DNA were given anti-CMV treatment.Results:CMV DNA( ) in recipients after operation enhanced the development of rejection. Ganciclovir therapy reduced the incidence of rejection.Conclusion:It is important to prevent and treat CMV infection in renal allograft recipients. |
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| Keywords: | Cytomegalovirus Infection Kidney Transplantation Graft Rejection |
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