| 和厚朴酚治疗妇科肿瘤的药理作用及其机制的研究进展 |
| |
| 引用本文： | 刘晓宁,张明发,沈雅琴.和厚朴酚治疗妇科肿瘤的药理作用及其机制的研究进展[J].现代药物与临床,2022,37(6):1420-1424. |
| |
| 作者姓名： | 刘晓宁 张明发 沈雅琴 |
| |
| 作者单位： | 天津市南开区中医医院, 天津 300191;上海美优制药有限公司, 上海 201204 |
| |
| 摘 要： | 全球女性癌症中1/3以上是妇科肿瘤，1/4以上死于妇科肿瘤。目前妇科肿瘤的治疗仍以手术和放疗为主，并用化疗药预防复发和转移。和厚朴酚是厚朴中主要活性成分，具有广泛的药理活性，抗肿瘤研究受到了很大的关注。综述了和厚朴酚抗乳腺癌、抗卵巢癌、抗宫颈癌的药理作用及其机制的研究进展，为其在防治妇科肿瘤中的研究提供参考。
|
| 关 键 词： | 和厚朴酚 抗肿瘤 乳腺癌 卵巢癌 宫颈癌 机制 |
| 收稿时间： | 2022/3/21 0:00:00 |
Research advance on pharmacologic effect and its mechanism of honokiol against gynecology cancer |
| |
| LIU Xiao-ning,ZHANG Ming-f,SHEN Ya-qin.Research advance on pharmacologic effect and its mechanism of honokiol against gynecology cancer[J].Drugs & Clinic,2022,37(6):1420-1424. |
| |
| Authors: | LIU Xiao-ning ZHANG Ming-f SHEN Ya-qin |
| |
| Institution: | Nankai Traditional Chinese Medicine Hospital, Tianjin 300191, China;Shanghai Meiyou Pharmaceutical Co., Ltd., Shanghai 201204, China |
| |
| Abstract: | More than 1/3 of female cancer patients in the world are gynecological tumors, and more than 1/4 die from gynecological tumors. At present, the treatment of gynecological tumors is still mainly surgery and radiotherapy, and chemotherapy drugs are used to prevent recurrence and metastasis. Honokiol is the main active ingredient in Magnoliae Officinalis Cortex, which has a wide range of pharmacological activities, and its anti-tumor research has received great attention. This paper reviews the research progress of the pharmacological effects and its mechanisms of honokiol against breast cancer, ovarian cancer, and cervical cancer, and provides a reference for its research in the prevention and treatment of gynecological tumors. |
| |
| Keywords: | honokiol anticancer mammary cancer ovarian carcinoma cervical carcinoma mechanism |
|
| 点击此处可从《现代药物与临床》浏览原始摘要信息 |
| 点击此处可从《现代药物与临床》下载免费的PDF全文 |
|
