Successful treatment of severe recalcitrant psoriasis with combination infliximab and methotrexate |
| |
| Authors: | Kirby B Marsland A M Carmichael A J Griffiths C E |
| |
| Affiliation: | Dermatology Centre, University of Manchester, Hope Hospital, Salford, Manchester, UK. bkirby@fs1.ho.man.ac.uk |
| |
| Abstract: | Plaques of psoriasis contain increased levels of cytokines, including tumour necrosis factor-alpha (TNF-alpha), which are thought to be essential to the maintenance of the psoriatic process. We report the successful treatment of severe, recalcitrant psoriasis when infliximab (a monoclonal antibody to TNF-alpha) was used in combination with methotrexate. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
