高能正电子成像在结肠肿瘤诊断中的应用

目的评估高能正电子成像技术在结肠肿瘤诊断中的临床实用价值.方法对25例临床诊断结肠肿瘤的患者,于手术前进行高能正电子成像检查.通过定性和半定量分析法对照病理检查结果,研究其对肿瘤病灶检测的灵敏度和特异度、良恶性病灶靶本比值(T/B)之间的差异.结果高能正电子成像对结肠肿瘤检测的灵敏度为9474%,特异度为83.33%.恶性病灶的T/B值3.63±1.18,显著高于良性病灶的1.42±0.35(P＜0.01).结论高能正电子成像对结肠肿瘤的诊断具有重要的实用价值.

Clinical Implication of High Energy Positron Imaging in the Diagnosis of ColonTumor

Objective To evaluate the value of high energy positron imaging in the diagnosis of colon neoplasm. Methods Twenty-five patients with recently diagnosed or suspected colon tumors were examined with high energy positron imaging before operation. According to pathological diagnosis, we analyzed the sensitivity and specificity of high energy positron imaging for detecting the primary metastastic lesions, and the ratio of target-to-background counts between benign and malignant tumors. Results The sensitivity and specificity of high energy positron imaging were 94.74% and 83.33% in detecting the primary lesions, respectively. The ratio of T/B of malignant lesions was significantly higher than that of benign lesions. Conclusion High energy positron imaging represents a new and non-invasive diagnostic technique with high sensitivity and specificity for the diagnosis of colon tumor.