周围型肺鳞癌与周围型肺腺癌的螺旋CT动态增强对照

目的 对照分析周围型肺鳞癌与周围型肺腺癌的CT动态增强表现,探讨CT动态增强对鉴别周围型肺鳞癌与周围型肺腺癌的价值。方法 对30例周围型肺鳞癌与40例周围型肺腺癌进行CT动态增强扫描,测量增强前后各次扫描时的CT增强值,根据CT增强值绘出动态增强曲线,并观察增强模式。结果 周围型肺腺癌的增强峰值与峰值到达时间与周围型肺鳞癌相比,差异无统计学意义（P〉0．05）。当病灶〉3cm时,两组的增强模式差异无统计学意义（P〉0．05）;当病灶≤3cm时,两组的增强模式差异有统计学意义（P〈0．05）,腺癌以均匀增强为主,鳞癌以不均匀增强或周边增强为主。结论 根据增强峰值与峰值到达时间不能鉴别周围型肺鳞癌与周围型肺腺癌;当病灶≤3cm时,周围型肺鳞癌的增强模式不同于周围型腺癌。

Comparison by dynamic enhancement in spiral CT to differentiate peripheral squamous cell carcinoma from adenocarcinoma of the lung

Objective To compare the manifestations of peripheral lung squamous cell carcinoma by CT dynamic enhancement with that of adenocarcinoma, and evaluate the difference of CT dynamic enhancement to distinguish peripheral lung squamous cell carcinomas from adenocarcinoma. Methods Thirty peripheral lung squamous cell carcinomas and 40 adenocarcinomas were examined with dynamic contrasted CT, enhancement at various phases recorded, based on which the time-intensity curves were produced. The enhancement patterns were compared and analyzed. Results There was no statistically significant difference in the enhancement degree and peak time between peripheral lung squamous cell carcinoma and adenocarcinoma (P>0.05). The difference in enhancement pattern between these two different types of carcinoma was not statistically significant when the lesion was larger than 3 cm in diameter(P>0.05), whereas it became statistically significant when the lesion is less than 3 cm (P<0.05). Most of the squamous cell carcinoma showed heterogenous enhancement or peripheral enhancement in the tumor zone, however, most of the adenocarcinomas had homogenous enhancement. Conclusion The maximum enhancement and the peak time are not helpful in differentiating peripheral lung squamous cell carcinoma from adenocarcinoma. When the lesion is less than 3 cm in diameter, the enhancement pattern of peripheral squamous cell carcinomas is different from that of adenocarcinoma.