牙周袋内挥发性硫化物对牙周基础治疗效果的影响

目的：初步探讨牙周袋内挥发性硫化物（volatile sulphur cornpounds，VSC）水平与慢性牙周炎（chronic periodontitis，CP）炎症程度的关系及其对牙周基础治疗效果的影响。方法：选择25例CP患者（男13例、女12例，平均年龄35岁），在治疗前用金刚牙周诊断仪检测硫化物水平，并记录探诊深度、附着丧失、探诊出血等临床指标，基础治疗后3个月再次检查各项临床指标。结果：在治疗前，浅、中、深袋组的VSC阳性位点率分别为17．1％、52．3％、86．0％，各组间差异有显著性（P〈0．001）；各个水平级别的VSC在不同袋深组中均有分布，各组中VSC水平〈1．0的位点占绝大多数，随着袋深的增加，高水平的VSC位点比例逐渐增高，差异有显著性（P〈0．01）。治疗后，VSC阴性位点的各项临床指标均较治疗前有显著性改善；VSC阳性位点的临床指标虽较治疗前有改善，但探诊深度、附着丧失的改善均明显差于阴性位点。结论：VSC水平可以在一定程度上反映牙周的炎症程度，并影响牙周基础治疗的效果。VSC的检测可以作为评判牙周炎活动性及预后的辅助手段。

Impact of volatile sulphur compounds in periodontal pockets on initial periodontal therapy

OBJECTIVE: To investigate the relationship of volatile sulphur compounds((VSC)levels in periodontal pockets with severity of periodontitis, and the impact of VSC on the result of initial periodontal therapy. METHODS: Twenty-five patients with chronic periodontitis(CP)(13 males and 12 females with average age of 35) were included in this study. Clinical periodontal parameters, plaque index, probing depth(PD), attachment loss(AL), and bleeding on probing(BOP) were recorded before and 3 months after the initial therapy. VSC levels were measured with a portable monitor in a digital score ranging from 0.0 to 5.0. All of 5 054 sites for 840 teeth were included in this study. RESULT: Before treatment the percentage of VSC-positive sites was 17.1%, 52.3% and 86.0% for shallow (PD<3 mm), moderate(PD 4-6 mm) and deep (PD>7 mm) pocket, respectively (P<0.001). In most VSC-positive sites the VSC levels were<1.0. Percentage of sites with a high VSC levels was significantly different among three groups (P<0.01). All clinical parameters in VSC-negative sites were reduced significantly following the initial therapy. The reduction of PD and AL in VSC-positive sites by treatment was less marked than that in VSC-negative sites. Conclusion: VSC in periodontal pockets may be a potential indictor for detecting severity of CP and a useful predictor for therapeutic success.