60岁以上老年人血清性激素水平、血脂分析与冠心病关系的探讨

目的：为了探讨60岁以上老年人血清性激素、血脂分析与冠心病的关系。方法：生化法和化学发光免疫分析检测了75例冠心病和88例正常对照组中血清胆固醇（total cholesterol，TC）、三酰甘油（triglycerides，TG）、低密度脂蛋白胆固醇（low density lipoprotein cholesterol，LDL—C）、高密度脂蛋白胆固醇（high density lipoprotein cholesterol，HDL—C）和性激素（sex hormones，estrodial，E2；testosterone，T）水平。结果：75例冠心病患者较之88例正常对照组血清TC、TG、LDL—C显著增高，而HDL-C明显降低；而30例女性冠心病患者较之36例女性正常对照组血清E2明显降低，45例男性冠心病患者较之52例男性正常对照组血清T明显降低。结论：60岁以上老年人血清性激素水平、血脂分析与冠心病存在着明显的相关关系。如及早治疗，可以明显改善老年人生活质量。

Study on the Serum Sex Hormones Levels and Lipids Profile in Patients Over 60 Years Old with Coronary Heart Disease

Objective To study the serum sex hormones levels and lipid profile in over 60 years old with atherosclertic coronary heart disease.Methods The levels of serum TC,TG,LDL-C,HDL-C(with biochemistry),E2 and T(with CLIA) were determined in 75 patients with coronary heart disease(all over 60 years old) and 88 controls.Results Serum TC,TG,LDL-C,levels in the patients with coronary heart disease were significantly higher than those in controls(P<0.05 or P<0.01),but HDL-C,E2 and T levels were significantly lower(P<0.05 or P<0.01).Conclusion Lowering of serum sex hormones levels and changes lipid profile readings were significant in older patients(over 60 years) with coronary heart disease.