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多吉美联合介入治疗原发性肝癌20例
引用本文:李枫,王峰,李军,杨新顺. 多吉美联合介入治疗原发性肝癌20例[J]. 世界华人消化杂志, 2010, 18(5)
作者姓名:李枫  王峰  李军  杨新顺
作者单位:大连医科大学附属第一医院介入治疗科,辽宁省大连市,116001;大连医科大学附属第一医院介入治疗科,辽宁省大连市,116001;大连医科大学附属第一医院介入治疗科,辽宁省大连市,116001;大连医科大学附属第一医院介入治疗科,辽宁省大连市,116001
摘    要:目的:对比多吉美单药治疗肝癌与联合介入治疗的效果.方法:回顾性分析20例系统服用多吉美的肝癌患者,其中单药治疗的7例,联合介入治疗的13例,随访方式采用门诊随访及住院随访,随访时间7-28 mo.主要研究终点为肿瘤反应率和肿瘤进展时间.结果:20例患者中,CR 4例,PR 10例,SD 4例,PD 2例,其中单药治疗组CR 0例,PR 3例,SD2例,PD 2例,单药治疗组及联合治疗组的中位肿瘤进展时间分别为16及48 wk.结论:多吉美联合肝癌介入治疗可增加肿瘤反应率,延长肿瘤进展时间.

关 键 词:多吉美  介入治疗  肝癌  疗效

Nexavar in combination with interventional therapy for hepatocellular carcinoma:a report of 20 cases
Feng Li,Feng Wang,Jun Li,Xin-Shun Yang. Nexavar in combination with interventional therapy for hepatocellular carcinoma:a report of 20 cases[J]. World Chinese Journal of Digestology, 2010, 18(5)
Authors:Feng Li  Feng Wang  Jun Li  Xin-Shun Yang
Affiliation:Feng Li,Feng Wang,Jun Li,Xin-Shun Yang,Department of Interventional Therapy,the First Affiliated Hospital of Dalian Medical University,Dalian 116001,Liaoning Province,China
Abstract:AIM:To analyze the efficacy of Nexavar alone and in combination with interventional therapy for hepatocellular carcinoma.METHODS:Twenty hepatocellular carcinoma patients,including 7 receiving Nexavar monotherapy and 13 receiving Nexavar in combination with interventional therapy,were retrospectively analyzed.All patients were followed up for 7-28 months.The primary study endpoint was tumor response rate and time to tumor progression (TTP).RESULTS:Of 20 patients,4 achieved a complete response (CR),10 achieve...
Keywords:Nexavar  Interventional therapy  Hepatocellular carcinoma  Efficacy  
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