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Clinical Performance of a New Transparent Chlorhexidine Gluconate Central Venous Catheter Dressing
Affiliation:1. Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands;2. Department of Pathology and Medical Biology, Medical Biology Section, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands;3. Department of Pathology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands;4. Nanomi B.V., Zutphenstraat 51, 7575 EJ, Oldenzaal, The Netherlands;1. Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA;;2. Sangamo BioSciences Inc., Richmond, CA;;3. Molecular Biology Interdepartmental PhD Program, University of California, Los Angeles, Los Angeles, CA;;4. Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL;;5. Department of General Internal Medicine and Health Services Research, University of California, Los Angeles, Los Angeles, CA; and;6. Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research, University of California, Los Angeles, Los Angeles, CA;3. From the Stony Brook Cancer Center and the Department of Medicine, Stony Brook University, Stony Brook, New York 11794-8155 and;4. the Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina 29403;1. College of Business, University of Colorado Colorado Springs, United States;2. Lally School of Management, Rensselaer Polytechnic Institute, United States;3. Department of Business Administration, College of Business, University of Illinois at Urbana-Champaign, United States
Abstract:As the sciences of vascular access and infection prevention rapidly advance healthcare professionals are often faced with new technologies designed to help, but which are often so complicated to use that they cause unforeseen problems. As a vascular access team at a major mid-western hospital, we evaluated the ease-of-use and the performance characteristics of a new transparent catheter dressing, 3M Tegaderm CHG IV Securement Dressing® (3M Health Care™, St. Paul, MN) containing the antimicrobial chlorhexidine gluconate (CHG), with a variety of central venous catheters insertion sites in comparison to a standard non-antimicrobial dressing Tegaderm® (3M Health Care™, St. Paul, MN). Following IRB approval, sixty-three consenting patients were enrolled and randomized; 33 in the CHG antimicrobial dressing group and 30 in the standard dressing group. Thirty six patients had peripherally inserted central catheters (PICCs), 20 had intrajugular insertions (IJ), and 7 had subclavian insertions. The new 3M Tegaderm CHG IV Securement Dressing® (3M Health Care™, St. Paul, MN) was evaluated for its ability to permit visualization of the insertion site, ease of use, ease of using correctly, ability to secure the catheter and absorb exudates and remain transparent.The new 3M Tegaderm CHG IV Securement Dressing® (3M Health Care™, St. Paul, MN) was found to be as easy to use in central venous catheter care clinical practice as the standard of care non-antimicrobial transparent adhesive dressing. No additional training or education was required to properly use it. This dressing was applied and removed like standard transparent adhesive dressings, but offered many advantages over standard dressings. Advantages include that it is antimicrobial, handles moderate bleeding, remains transparent and appears to offer greater catheter securement than the Tegaderm® (3M Health Care™, St. Paul, MN) standard dressing. The CHG gel pad also conformed well to the catheter.
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