Difficulties in Diagnosis and Management of Ectopic Cushing Syndrome |
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Institution: | 2. Department of Internal Medicine, Seoul National University Bundang Hospital, Gyeonggi-do, Korea;3. Department of Pathology, Seoul National University Bundang Hospital, Gyeonggi-do, Korea |
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Abstract: | A 18-year-old man presented to a local hospital with muscle weakness, facial edema, and a 6 kg weight gain over 2 months. After a complete work-up, he was diagnosed with pituitary Cushing syndrome and treated with a bilateral adrenalectomy for Cushing syndrome and pituitary radiotherapy for Nelson syndrome. Twenty-five years later, his ectopic source of adrenocorticotropic hormone was revealed as a pulmonary neuroendocrine tumor, and a pulmonary resection was performed. Subsequently, a biochemical and clinical remission including hyperpigmentation was achieved. |
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Keywords: | Neuroendocrine tumor Ectopic Cushing syndrome |
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