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Solitary meningeal recurrence in a patient with transitional cell carcinoma of the bladder with locally bulky disease at presentation
Authors:Santarossa  Sandra  Vaccher  Emanuela  Balestreri  Luca  Volpe  Rachele  Tirelli  Umberto
Affiliation:(1) Division of Medical Oncology and AIDS, Centro di Riferimento Oncologico, Italy;(2) Department of Radiology, Centro di Riferimento Oncologico, Italy;(3) Division of Pathology, Centro di Riferimento Oncologico, Aviano, Italy
Abstract:Patients with locally advanced transitional cell carcinoma (TCC)of the bladder are at high risk forsystemic relapse, with liver, bone and lung beingthe commonest sites of metastases.We report the case of a 52-year-old womanwith a solitary meningeal relapse, a rare siteof recurrence, after 8 months of complete remissionobtained with M-VEC for locally advanced TCC ofthe bladder. We speculate on the likely riskfactors related to this unusual site of recurrence.
Keywords:transitional cell carcinoma  meningeal recurrence  chemotherapy
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