良性前列腺增生相关的膀胱痉挛病因分析及治疗

目的:探讨与良性前列腺增生(BPH)有关的膀胱痉挛的发生原因,寻找有效的防治方法。方法:102例BPH患者术前均行尿流动力学检查;应用t检验及χ2检验分析BPH患者的国际前列腺症状评分(IPSS)、前列腺体积(Vp)、生活质量评分(QOL)、手术方式及尿流动力学各项指标与膀胱痉挛发生的相关性。结果:在102例患者尿流动力学检查结果的分类中,低顺应性膀胱和不稳定膀胱的膀胱痉挛发生率为32.1%(9/28例)和42.5%(13/20例)。开放式手术和经尿道前列腺电切术(TURP)后膀胱痉挛发生率分别是50.9%(26/51例)、23.3%(12/51例),两者相比差异有显著性(P<0.05)。结论:低顺应性膀胱、不稳定膀胱及开放手术易产生膀胱痉挛。TURP可以降低BPH术后的膀胱痉挛发生率。

Etiology and Treatment of Bladder Spasm Assouciated with Benign Prostatic Hyperplasia

OBJECTIVE: To investigate the etiology and treatment of bladder spasm associated with benign prostatic hyperplasia (BPH). METHODS: Urodynamic tests were performed in 102 cases of BPH before operation. The correlation of bladder spasm with aging, international prostate symptom score (IPSS), quality of life, prostatic volume, operation methods and urodynamic indexes was studied by t and chi2 tests. RESULTS: The incidences of bladder spasm in the lower compliant bladder and unstable bladder were 32.1% (9/28) and 42.5% (13/20), and those after suprapubic prostatectomy and transurethral resection of the prostate (TURP) were 50.9% (26/51) and 23.3% (12/51). There was significant difference between operation methods (P < 0.05). CONCLUSION: Bladder spasm easily develops in the lower compliant bladder and unstable bladder, especially after suprapubic prostatectomy. TURP might decrease the incidence of bladder spasm after BPH operation.