出国体检人员中可疑氯胺酮阳性病例确证分析

目的建立一种快速、灵敏的方法用于氯胺酮初筛为阳性后的确证。方法采用传统的液-液萃取法进行人体尿液样品前处理,并结合单四极杆气相色谱质谱联用法(GC/MS)对样品进行确证分析。结果该氯胺酮初筛阳性尿样在确证分析中未检出氯胺酮。被检尿样的GC/MS谱图中未见明显的氯胺酮色谱峰;而经质谱定性后发现谱图中有较高的麻黄素色谱峰。结论本研究建立的GC/MS分析方法对于毒品确证十分准确、有效,可推广应用于其它毒品初筛为阳性的进一步确证实验中。

Analysis of suspected case with ketamine positive among exit personel using drug affirming testing

Objective To establish a fast,sensitive affirming testing method to determine the result of ketamine in elementary drug testing.Methods Drug affirming testing was done using traditional liquid-liquid extraction as sample pretreatment and combining gas chromatograph-mass spectrometer（GC/MS） methods.Results The ketamine was not detected in drug affirming testing.There was no obvious ketamine peak in the chromatogram GC/MS methods.However the ephedrine peak can be observed distinctly in the chromatogram.Conclusion The new established GC/MS method is very exact and effective for ketamine affirming,so this method can be applied to other drug affirming testing.